# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5290158 | 22b | INH | 0 | ALA5233428 | Active | % | Homo sapiens | ||||
2. | ALA5290158 | 22b | IC50 | = | 50 | uM | ALA5233415 | 4.30 | nM | Homo sapiens | ||
3. | ALA5290158 | 22b | IC50 | = | 50 | uM | ALA5233414 | 4.30 | nM | Homo sapiens | ||
4. | ALA5290158 | 22b | IC50 | = | 50 | uM | ALA5233413 | 4.30 | nM | Homo sapiens | ||
5. | ALA5290158 | 22b | IC50 | = | 7.75 | uM | ALA5233412 | 5.11 | nM | Homo sapiens | ||
6. | ALA5290158 | 22b | IC50 | = | 50 | uM | ALA5233411 | 4.30 | nM | Homo sapiens | ||
7. | ALA5290158 | 22b | IC50 | = | 50 | uM | ALA5233410 | 4.30 | nM | Homo sapiens | ||
8. | ALA5290158 | 22b | MRT | = | 1.98 | hr | ALA5233409 | hr | ||||
9. | ALA5290158 | 22b | AUC | = | 1057 | ng.hr/ml | ALA5233408 | ng.hr.mL-1 | ||||
10. | ALA5290158 | 22b | Tmax | = | 0.25 | hr | ALA5233407 | hr | ||||
11. | ALA5290158 | 22b | t1/2 | = | 1.26 | hr | ALA5233406 | hr | ||||
12. | ALA5290158 | 22b | Cmax | = | 479 | ng/ml | ALA5233405 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | ALA5290158 | 22b | CLH | = | 10.3 | ml/min.g | ALA5233404 | ml/min.g | ||||
14. | ALA5290158 | 22b | CLH | = | 10.5 | ml/min.g | ALA5233403 | ml/min.g | ||||
15. | ALA5290158 | 22b | CLH | = | 27.6 | ml/min.g | ALA5233402 | ml/min.g | ||||
16. | ALA5290158 | 22b | t1/2 | = | 203.9 | min | ALA5233401 | hr | ||||
17. | ALA5290158 | 22b | t1/2 | = | 200.3 | min | ALA5233400 | hr | ||||
18. | ALA5290158 | 22b | t1/2 | = | 76 | min | ALA5233399 | hr | ||||
19. | ALA5290158 | 22b | IC50 | = | 1.64 | uM | ALA5233398 | 5.79 | nM | Homo sapiens | ||
20. | ALA5290158 | 22b | Activity | 0 | ALA5233396 | Active | Rattus norvegicus |