# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | γ-hydroxybutyric acid | GHB | EC50 | = | 5 | mM | ALA4481496 | nM | ||||
2. | γ-hydroxybutyric acid | GHB | Ki | = | 4.3 | uM | ALA4481483 | 5.37 | nM | Rattus norvegicus | ||
3. | γ-hydroxybutyric acid | GHB | Ki | > | 1000 | uM | ALA4481482 | nM | Rattus norvegicus | |||
4. | γ-hydroxybutyric acid | GHB | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
5. | γ-hydroxybutyric acid | GHB | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
6. | γ-hydroxybutyric acid | GHB | inhibition | = | -3.37 | % | ALA4808150 | % | Homo sapiens | |||
7. | γ-hydroxybutyric acid | GHB | inhibition | = | 1.38 | % | ALA4808149 | % | Homo sapiens | |||
8. | γ-hydroxybutyric acid | GHB | DILI_Concern | 0 | ALA4029350 | No-Dili-Concern | Homo sapiens | |||||
9. | γ-hydroxybutyric acid | GHB | DILI_severity_class | = | 0 | ALA4029349 | Homo sapiens | |||||
10. | γ-hydroxybutyric acid | GHB | pKi | = | 5.44 | ALA4020668 | 5.44 | nM | ||||
11. | γ-hydroxybutyric acid | GHB | Ki | = | 3.6 | uM | ALA4020668 | 5.44 | nM | |||
12. | γ-hydroxybutyric acid | GHB | Ki | = | 51 | uM | ALA5099990 | 4.29 | nM | Rattus norvegicus | ||
13. | γ-hydroxybutyric acid | GHB | Ki | = | 3 | uM | ALA5099989 | 5.52 | nM | Rattus norvegicus | ||
14. | γ-hydroxybutyric acid | GHB | Ki | = | 4.3 | uM | ALA5099988 | 5.37 | nM | Rattus norvegicus | ||
15. | γ-hydroxybutyric acid | GHB | Ki | = | 4.3 | uM | ALA5166512 | 5.37 | nM | Homo sapiens | ||
16. | γ-hydroxybutyric acid | GHB | INH | 0 | ALA2432569 | Dose-dependent effect | % | |||||
17. | γ-hydroxybutyric acid | GHB | IC50 | = | 1.14 | uM | ALA2432569 | 5.94 | nM | |||
18. | γ-hydroxybutyric acid | GHB | pIC50 | = | 5.94 | ALA2432569 | 5.94 | nM | ||||
19. | γ-hydroxybutyric acid | GHB | Ki | = | 4.3 | uM | ALA2432575 | 5.37 | nM | |||
20. | γ-hydroxybutyric acid | GHB | BPR | = | 0.2 | ALA2432566 |