# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA170758 | 5o | Inhibition | = | 70.79 | % | ALA3436044 | % | Leishmania mexicana | |||
2. | ALA170758 | 5o | Inhibition | = | 90.01 | % | ALA3436043 | % | Plasmodium falciparum | |||
3. | ALA170758 | 5o | Inhibition | = | 89.42 | % | ALA3436042 | % | Homo sapiens | |||
4. | ALA170758 | 5o | IC50 | = | 2022 | nM | ALA3436041 | 5.69 | nM | Homo sapiens | ||
5. | ALA170758 | 5o | IC50 | = | 1390 | nM | ALA3436040 | 5.86 | nM | Leishmania mexicana | ||
6. | ALA170758 | 5o | IC50 | = | 1482 | nM | ALA3436039 | 5.83 | nM | Plasmodium falciparum | ||
7. | ALA170758 | 5o | MIC | = | 0.025 | ug ml-1 | ALA3739020 | ug.mL-1 | Candida albicans | |||
8. | ALA170758 | 5o | Tmax | = | 1.8 | hr | ALA3739019 | hr | Canis lupus familiaris | |||
9. | ALA170758 | 5o | Ki | = | 0.3 | pM | ALA3738282 | nM | Homo sapiens | |||
10. | ALA170758 | 5o | Ki | = | 0.03 | nM | ALA3738284 | 10.52 | nM | Candida albicans | ||
11. | ALA170758 | 5o | GI50 | = | 0.74 | nM | ALA3738286 | nM | ||||
12. | ALA170758 | 5o | t1/2 | = | 2.8 | hr | ALA3738287 | hr | Canis lupus familiaris | |||
13. | ALA170758 | 5o | t1/2 | = | 4 | hr | ALA3739003 | hr | Canis lupus familiaris | |||
14. | ALA170758 | 5o | Cmax | = | 0.17 | ug ml-1 | ALA3739004 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
15. | ALA170758 | 5o | Vd | = | 9.3 | L/Kg | ALA3739005 | L.kg-1 | Canis lupus familiaris | |||
16. | ALA170758 | 5o | F | = | 49 | % | ALA3739006 | % | Canis lupus familiaris | |||
17. | ALA170758 | 5o | Inhibition | = | 61 | % | ALA1054504 | % | Homo sapiens | |||
18. | ALA170758 | 5o | IFI | = | 3.73 | % | ALA1054505 | % | ||||
19. | ALA170758 | 5o | Inhibition | = | 95 | % | ALA1054501 | % | Plasmodium falciparum | |||
20. | ALA170758 | 5o | Inhibition | = | 95 | % | ALA1054500 | % | Plasmodium falciparum |