# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA368810 | 13, NSC-31867 | Inhibition | = | -14.32 | % | ALA4296190 | Average; N=2; Conc=25 Um ; | % | Cryptococcus neoformans | ||
2. | ALA368810 | 13, NSC-31867 | Inhibition | = | -18.85 | % | ALA4296193 | Average; N=2; Conc=25 Um ; | % | Acinetobacter baumannii | ||
3. | ALA368810 | 13, NSC-31867 | Inhibition | = | 23.6 | % | ALA4296192 | Average; N=2; Conc=25 Um ; | % | Staphylococcus aureus | ||
4. | ALA368810 | 13, NSC-31867 | Inhibition | = | 2.52 | % | ALA4296189 | Average; N=2; Conc=25 Um ; | % | Candida albicans | ||
5. | ALA368810 | 13, NSC-31867 | Inhibition | = | 10.29 | % | ALA4296187 | Average; N=2; Conc=25 Um ; | % | Pseudomonas aeruginosa | ||
6. | ALA368810 | 13, NSC-31867 | Inhibition | = | -6.31 | % | ALA4296186 | Average; N=2; Conc=25 Um ; | % | Klebsiella pneumoniae | ||
7. | ALA368810 | 13, NSC-31867 | Inhibition | = | 9.72 | % | ALA4296783 | Average; N=2; Conc=25 Um ; | % | Escherichia coli | ||
8. | ALA368810 | 13, NSC-31867 | Drug metabolism | 0 | ALA3860222 | Metabolite_Detected | ||||||
9. | ALA368810 | 13, NSC-31867 | Drug metabolism | 0 | ALA3860221 | Metabolite_Detected | ||||||
10. | ALA368810 | 13, NSC-31867 | Drug metabolism | 0 | ALA3860220 | Metabolite_Detected | ||||||
11. | ALA368810 | 13, NSC-31867 | Stability | 0 | ALA3860219 | Not Determined | % | |||||
12. | ALA368810 | 13, NSC-31867 | t1/2 | = | 3.1 | min | ALA3860218 | hr | ||||
13. | ALA368810 | 13, NSC-31867 | t1/2 | = | 3.5 | min | ALA3860217 | hr | ||||
14. | ALA368810 | 13, NSC-31867 | CLH | = | 452 | uL/min | ALA3860216 | uL/min | ||||
15. | ALA368810 | 13, NSC-31867 | CLH | = | 393 | uL/min | ALA3860215 | uL/min | ||||
16. | ALA368810 | 13, NSC-31867 | Ratio | = | 0.51 | ALA3860214 | ||||||
17. | ALA368810 | 13, NSC-31867 | Drug recovery | = | 95.1 | % | ALA3860213 | % | ||||
18. | ALA368810 | 13, NSC-31867 | Papp | = | 32.4 | ucm/s | ALA3860212 | ucm/s | ||||
19. | ALA368810 | 13, NSC-31867 | logD | = | 3.5 | ALA3860211 | ||||||
20. | ALA368810 | 13, NSC-31867 | solubility | = | 37.5 | uM | ALA3860210 | nM |