Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA23541	(+/-)1 (racemic)	IC50	=	32	uM	ALA1639364	4.50	nM	Homo sapiens
2.	ALA23541	(+/-)1 (racemic)	IC50	=	22	uM	ALA1639363	4.66	nM	Homo sapiens
3.	ALA23541	(+/-)1 (racemic)	IC50	=	26	uM	ALA1639362	4.58	nM
4.	ALA23541	(+/-)1 (racemic)	ED50	=	0.2	mg/kg/day	ALA1639352		mg/kg/day	Macaca mulatta
5.	ALA23541	(+/-)1 (racemic)	ED50	=	2	mg/kg/day	ALA1639351		mg/kg/day	Rattus norvegicus
6.	ALA23541	(+/-)1 (racemic)	ED50	=	1	mg/kg/day	ALA1639350		mg/kg/day	Cricetinae
7.	ALA23541	(+/-)1 (racemic)	ED50	=	2	mg/kg/day	ALA1639349		mg/kg/day	Cricetinae
8.	ALA23541	(+/-)1 (racemic)	ED50	=	2.2	mg/kg/day	ALA883745		mg/kg/day	Cricetinae gen. sp.
9.	ALA23541	(+/-)1 (racemic)	ED100	=	1	MPK	ALA730166		MPK	Cercopithecidae
10.	ALA23541	(+/-)1 (racemic)	ED50	=	2.2	MPK	ALA694520		mg.kg-1	Cricetinae gen. sp.
11.	ALA23541	(+/-)1 (racemic)	Reduction	=	-78	%	ALA693040		%	Cricetinae gen. sp.
12.	ALA23541	(+/-)1 (racemic)	ED50	=	0.1	mg kg-1	ALA667933		mg.kg-1	Canis lupus familiaris
13.	ALA23541	(+/-)1 (racemic)	ED50	=	0.2	mg kg-1	ALA733238		mg.kg-1	Cercopithecidae
14.	ALA23541	(+/-)1 (racemic)	ED50	=	2	mg kg-1	ALA780376		mg.kg-1	Rattus norvegicus
15.	ALA23541	(+/-)1 (racemic)	ED50	=	2.2	mg kg-1	ALA694529		mg.kg-1	Cricetinae gen. sp.
16.	ALA23541	(+/-)1 (racemic)	Change in cholesterol	=	-43	%	ALA693582		%	Cricetulus griseus
17.	ALA23541	(+/-)1 (racemic)	Change in cholesterol	=	-93	%	ALA692410		%	Cricetulus griseus
18.	ALA23541	(+/-)1 (racemic)	IC50	=	26000	nM	ALA643830	4.58	nM	Homo sapiens
19.	ALA23541	(+/-)1 (racemic)	Change in cholesterol	=	-21	%	ALA693582		%	Cricetulus griseus
20.	ALA23541	(+/-)1 (racemic)	Change in cholesterol	=	60	%	ALA692410		%	Cricetulus griseus