| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1349 | Valaciclovir | solubility | = | 174 | mg/ml | ALA5247088 | ug.mL-1 | ||||
| 2. | ALA1349 | Valaciclovir | F | = | 54 | % | ALA5247010 | % | ||||
| 3. | ALA1349 | Valaciclovir | inhibition | = | -5.07 | % | ALA4808150 | % | Homo sapiens | |||
| 4. | ALA1349 | Valaciclovir | inhibition | = | 8.54 | % | ALA4808149 | % | Homo sapiens | |||
| 5. | ALA1349 | Valaciclovir | Hit score | = | 0.031 | ALA4303810 | Severe acute respiratory syndrome coronavirus 2 | |||||
| 6. | ALA1349 | Valaciclovir | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
| 7. | ALA1349 | Valaciclovir | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
| 8. | ALA1349 | Valaciclovir | inhibition | = | -0.2 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 9. | ALA1349 | Valaciclovir | LogD7.4 | -1.3 | ALA3301363 | |||||||
| 10. | ALA1349 | Valaciclovir | DILI_Concern | 0 | ALA4029350 | Less-Dili-Concern | Homo sapiens | |||||
| 11. | ALA1349 | Valaciclovir | DILI_severity_class | = | 3 | ALA4029349 | Homo sapiens | |||||
| 12. | ALA1349 | Valaciclovir | Hepatotoxicity (mechanism) | 0 | ALA3137740 | Dose-dependant | ||||||
| 13. | ALA1349 | Valaciclovir | Hepatotoxicity (time to onset) | 0 | ALA3137739 | 10 days | ||||||
| 14. | ALA1349 | Valaciclovir | Hepatotoxicity (comment) | 0 | ALA3137738 | |||||||
| 15. | ALA1349 | Valaciclovir | Hepatotoxicity (successful reintroduction) | 0 | ALA3137737 | |||||||
| 16. | ALA1349 | Valaciclovir | Hepatotoxicity (animal toxicity known) | 0 | ALA3137736 | |||||||
| 17. | ALA1349 | Valaciclovir | Hepatotoxicity (benign tumour) | = | 0 | ALA3137735 | references out of a total of 3 | |||||
| 18. | ALA1349 | Valaciclovir | Hepatotoxicity (malignant tumour) | = | 0 | ALA3137734 | references out of a total of 3 | |||||
| 19. | ALA1349 | Valaciclovir | Hepatotoxicity (steatosis) | = | 0 | ALA3137733 | references out of a total of 3 | |||||
| 20. | ALA1349 | Valaciclovir | Hepatotoxicity (association with vascular disease) | = | 0 | ALA3137732 | references out of a total of 3 |
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