| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA368876 | MB243 | IC50 | = | 16 | nM | ALA828110 | 7.80 | nM | Homo sapiens | ||
| 2. | ALA368876 | MB243 | Activation | = | 11 | % | ALA826582 | % | ||||
| 3. | ALA368876 | MB243 | IC50 | = | 1600 | nM | ALA828109 | 5.80 | nM | Homo sapiens | ||
| 4. | ALA368876 | MB243 | cAMP accumulation | = | 85 | % | ALA825400 | % | Homo sapiens | |||
| 5. | ALA368876 | MB243 | EC50 | = | 350 | nM | ALA834409 | 6.46 | nM | Homo sapiens | ||
| 6. | ALA368876 | MB243 | IC50 | = | 16 | nM | ALA828110 | 7.80 | nM | Homo sapiens | ||
| 7. | ALA368876 | MB243 | IC50 | = | 1700 | nM | ALA828108 | 5.77 | nM | Homo sapiens | ||
| 8. | ALA368876 | MB243 | cAMP accumulation | = | 32 | % | ALA825403 | % | Homo sapiens | |||
| 9. | ALA368876 | MB243 | EC50 | = | 1900 | nM | ALA834411 | 5.72 | nM | Homo sapiens | ||
| 10. | ALA368876 | MB243 | cAMP accumulation | = | 11 | % | ALA825401 | % | Homo sapiens | |||
| 11. | ALA368876 | MB243 | cAMP accumulation | = | 87 | % | ALA825402 | % | Homo sapiens | |||
| 12. | ALA368876 | MB243 | Activity | = | 21.2 | % | ALA834924 | % | Rattus norvegicus | |||
| 13. | ALA368876 | MB243 | T max | = | 5 | hr | ALA841036 | hr | ||||
| 14. | ALA368876 | MB243 | T1/2 | = | 1.3 | hr | ALA839079 | hr | ||||
| 15. | ALA368876 | MB243 | Vdss | = | 1.2 | l kg-1 | ALA840684 | L.kg-1 | ||||
| 16. | ALA368876 | MB243 | Clearance | = | 15.7 | ml min-1 kg-1 | ALA839371 | mL.min-1.kg-1 | ||||
| 17. | ALA368876 | MB243 | F | = | 11 | % | ALA851014 | % | ||||
| 18. | ALA368876 | MB243 | T max | = | 0.75 | hr | ALA841039 | hr | ||||
| 19. | ALA368876 | MB243 | T1/2 | = | 4.1 | hr | ALA840021 | hr | ||||
| 20. | ALA368876 | MB243 | Vdss | = | 1.2 | l kg-1 | ALA840686 | L.kg-1 |
The page will load shortly, Thanks for your patience!