| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA183129 | 1c (stereoisomer of comp. 1d) | CLtot | = | 141.8 | ml min-1 kg-1 | ALA876445 | mL.min-1.kg-1 | ||||
| 2. | ALA183129 | 1c (stereoisomer of comp. 1d) | T1/2 | = | 1.3 | mg kg-1 | ALA840618 | mg kg-1 | ||||
| 3. | ALA183129 | 1c (stereoisomer of comp. 1d) | AUC | = | 4.2 | ng hr-1 ml-1 | ALA840380 | ng.hr.mL-1 | ||||
| 4. | ALA183129 | 1c (stereoisomer of comp. 1d) | Cmax | = | 4.2 | ng ml-1 | ALA839102 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 5. | ALA183129 | 1c (stereoisomer of comp. 1d) | Selectivity | > | 200 | ALA825476 | Homo sapiens | |||||
| 6. | ALA183129 | 1c (stereoisomer of comp. 1d) | EC50 | > | 100 | nM | ALA834456 | nM | Homo sapiens | |||
| 7. | ALA183129 | 1c (stereoisomer of comp. 1d) | Selectivity | = | 40 | ALA825475 | Homo sapiens | |||||
| 8. | ALA183129 | 1c (stereoisomer of comp. 1d) | EC50 | = | 20 | nM | ALA834455 | 7.70 | nM | Homo sapiens | ||
| 9. | ALA183129 | 1c (stereoisomer of comp. 1d) | F | = | 20.3 | % | ALA851153 | % | ||||
| 10. | ALA183129 | 1c (stereoisomer of comp. 1d) | CLtot | = | 24.2 | ml min-1 kg-1 | ALA850277 | mL.min-1.kg-1 | ||||
| 11. | ALA183129 | 1c (stereoisomer of comp. 1d) | T1/2 | = | 8.1 | hr | ALA826141 | hr | ||||
| 12. | ALA183129 | 1c (stereoisomer of comp. 1d) | AUC | = | 140.1 | ng hr-1 ml-1 | ALA840383 | ng.hr.mL-1 | ||||
| 13. | ALA183129 | 1c (stereoisomer of comp. 1d) | Cmax | = | 52.6 | ng ml-1 | ALA839103 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA183129 | 1c (stereoisomer of comp. 1d) | F | = | 1.1 | % | ALA851150 | % | ||||
| 15. | ALA183129 | 1c (stereoisomer of comp. 1d) | EC50 | = | 0.5 | nM | ALA834457 | 9.30 | nM | Homo sapiens |
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