# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA364841 | 3g | F | = | 34 | % | ALA1821240 | % | Rattus norvegicus | |||
2. | ALA364841 | 3g | Vdss | = | 1800 | L/Kg | ALA1821239 | L.kg-1 | Rattus norvegicus | |||
3. | ALA364841 | 3g | t1/2 | = | 5.4 | hr | ALA1821238 | hr | Rattus norvegicus | |||
4. | ALA364841 | 3g | t1/2 | = | 9.8 | hr | ALA1821237 | hr | Rattus norvegicus | |||
5. | ALA364841 | 3g | CL | = | 2.4 | ml/min.kg | ALA1821235 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA364841 | 3g | Cmax | = | 3.5 | ug ml-1 | ALA1821236 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA364841 | 3g | AUC | = | 24.3 | microg.hr/mL | ALA1821232 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA364841 | 3g | AUC | = | 7.2 | microg.hr/mL | ALA1821231 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA364841 | 3g | Ki | = | 260 | nM | ALA1821230 | 6.58 | nM | Homo sapiens | ||
10. | ALA364841 | 3g | Ki | = | 3100 | nM | ALA1821229 | 5.51 | nM | Mus musculus | ||
11. | ALA364841 | 3g | IC50 | = | 2.4 | nM | ALA1821228 | 8.62 | nM | Mus musculus | ||
12. | ALA364841 | 3g | Ki | = | 16 | nM | ALA1821227 | 7.80 | nM | Mus musculus | ||
13. | ALA364841 | 3g | Ki | = | 37 | nM | ALA1821226 | 7.43 | nM | Homo sapiens | ||
14. | ALA364841 | 3g | Ki | > | 10000 | nM | ALA1821225 | nM | Mus musculus | |||
15. | ALA364841 | 3g | Ki | = | 1700 | nM | ALA1821224 | 5.77 | nM | Mus musculus | ||
16. | ALA364841 | 3g | Ki | = | 99 | nM | ALA1821223 | 7.00 | nM | Mus musculus | ||
17. | ALA364841 | 3g | Ki | = | 6200 | nM | ALA1821222 | 5.21 | nM | Mus musculus | ||
18. | ALA364841 | 3g | INH | = | 41 | % | ALA1816455 | % | Cavia porcellus | |||
19. | ALA364841 | 3g | INH | = | 23 | % | ALA1816454 | % | Cavia porcellus | |||
20. | ALA364841 | 3g | Ratio Ki | = | 2.3 | ALA1815367 |