| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA198075 | (-)-2 | solubility | = | 160 | ug ml-1 | ALA3624874 | ug.mL-1 | ||||
| 2. | ALA198075 | (-)-2 | solubility | < | 1 | ug ml-1 | ALA3627380 | ug.mL-1 | ||||
| 3. | ALA198075 | (-)-2 | Activity | = | 1.1 | % | ALA3624885 | % | Homo sapiens | |||
| 4. | ALA198075 | (-)-2 | Activity | = | 24.3 | % | ALA3625014 | % | Homo sapiens | |||
| 5. | ALA198075 | (-)-2 | Activity | = | 8.1 | % | ALA3625013 | % | Homo sapiens | |||
| 6. | ALA198075 | (-)-2 | Activity | = | 66.5 | % | ALA3625012 | % | Homo sapiens | |||
| 7. | ALA198075 | (-)-2 | AUC | = | 52.7 | ng.hr/ml | ALA3624882 | ng.hr.mL-1 | Mus musculus | |||
| 8. | ALA198075 | (-)-2 | F | = | 9.9 | % | ALA3624881 | % | Mus musculus | |||
| 9. | ALA198075 | (-)-2 | CL | = | 19 | L/hr/kg | ALA3624875 | mL.min-1.kg-1 | Mus musculus | |||
| 10. | ALA198075 | (-)-2 | beta t1/2 | = | 0.9 | hr | ALA3624876 | hr | Mus musculus | |||
| 11. | ALA198075 | (-)-2 | Vdss | = | 16.3 | L/Kg | ALA3624877 | L.kg-1 | Mus musculus | |||
| 12. | ALA198075 | (-)-2 | AUC | = | 53.2 | ng.hr/ml | ALA3624878 | ng.hr.mL-1 | Mus musculus | |||
| 13. | ALA198075 | (-)-2 | Cmax | = | 75.8 | ng/ml | ALA3624879 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 14. | ALA198075 | (-)-2 | beta t1/2 | 0 | ALA3624880 | Not Determined | Mus musculus | |||||
| 15. | ALA198075 | (-)-2 | IC50 | = | 0.94 | nM | ALA3627286 | 9.03 | nM | Homo sapiens | ||
| 16. | ALA198075 | (-)-2 | IC50 | = | 1.04 | nM | ALA3627287 | 8.98 | nM | Homo sapiens | ||
| 17. | ALA198075 | (-)-2 | IC50 | = | 1.26 | nM | ALA3627288 | 8.90 | nM | |||
| 18. | ALA198075 | (-)-2 | IC50 | = | 0.86 | nM | ALA3627292 | 9.07 | nM | Homo sapiens | ||
| 19. | ALA198075 | (-)-2 | IC50 | = | 2.55 | nM | ALA3627291 | 8.59 | nM | Homo sapiens | ||
| 20. | ALA198075 | (-)-2 | IC50 | = | 0.83 | nM | ALA3627290 | 9.08 | nM |
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