| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA197595 | 33a | ED50 | = | 2.2 | mg/kg/day | ALA5140956 | mg/kg/day | Rattus norvegicus | |||
| 2. | ALA197595 | 33a | Activity | = | 67 | % | ALA5140956 | % | Rattus norvegicus | |||
| 3. | ALA197595 | 33a | IC50 | = | 0.11 | uM | ALA5140955 | 6.96 | nM | Homo sapiens | ||
| 4. | ALA197595 | 33a | Ki | = | 6.2 | nM | ALA5140913 | 8.21 | nM | Rattus norvegicus | ||
| 5. | ALA197595 | 33a | Ki | = | 4.6 | nM | ALA5140896 | 8.34 | nM | Homo sapiens | ||
| 6. | ALA197595 | 33a | ED50 | = | 2.2 | mg kg-1 | ALA858789 | mg.kg-1 | Rattus norvegicus | |||
| 7. | ALA197595 | 33a | CL | 0 | ALA858851 | Not Determined | Rattus norvegicus | |||||
| 8. | ALA197595 | 33a | T1/2 | 0 | ALA858850 | Not Determined | Rattus norvegicus | |||||
| 9. | ALA197595 | 33a | AUC | = | 2582 | ng.hr/ml | ALA858849 | ng.hr.mL-1 | Rattus norvegicus | |||
| 10. | ALA197595 | 33a | Cmax | = | 96 | ng/ml | ALA858848 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 11. | ALA197595 | 33a | T1/2 | = | 11.2 | hr | ALA858846 | hr | Rattus norvegicus | |||
| 12. | ALA197595 | 33a | AUC | = | 43215 | ng.hr/ml | ALA858845 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA197595 | 33a | Cmax | = | 1561 | ng/ml | ALA858844 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 14. | ALA197595 | 33a | CL | = | 133 | mL/hr.kg | ALA858843 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 15. | ALA197595 | 33a | T1/2 | = | 12.5 | hr | ALA858842 | hr | Rattus norvegicus | |||
| 16. | ALA197595 | 33a | AUC | = | 21952 | ng.hr/ml | ALA858841 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA197595 | 33a | Cmax | = | 702 | ng/ml | ALA858795 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 18. | ALA197595 | 33a | Ki | > | 100000 | nM | ALA858794 | nM | Homo sapiens | |||
| 19. | ALA197595 | 33a | Ki | > | 100000 | nM | ALA858793 | nM | Homo sapiens | |||
| 20. | ALA197595 | 33a | Ki | = | 3300 | nM | ALA858792 | 5.48 | nM | Rattus norvegicus |
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