# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA201782 | (-)-34a | PPB | = | 85 | % | ALA1023821 | % | Homo sapiens | |||
2. | ALA201782 | (-)-34a | PPB | = | 85 | % | ALA1023820 | % | Oryctolagus cuniculus | |||
3. | ALA201782 | (-)-34a | PPB | = | 85 | % | ALA1023819 | % | Rattus norvegicus | |||
4. | ALA201782 | (-)-34a | Ratio IC50 | = | 53 | ALA1023833 | ||||||
5. | ALA201782 | (-)-34a | Selectivity ratio | = | 940 | ALA1023826 | ||||||
6. | ALA201782 | (-)-34a | Selectivity ratio | > | 36000 | ALA1023825 | ||||||
7. | ALA201782 | (-)-34a | Selectivity ratio | = | 780 | ALA1023824 | ||||||
8. | ALA201782 | (-)-34a | IC50 | = | 16 | nM | ALA1023832 | 7.80 | nM | |||
9. | ALA201782 | (-)-34a | IC50 | = | 0.32 | nM | ALA1023823 | 9.49 | nM | Oryctolagus cuniculus | ||
10. | ALA201782 | (-)-34a | IC50 | = | 0.28 | nM | ALA1023822 | 9.55 | nM | |||
11. | ALA201782 | (-)-34a | F | = | 78 | % | ALA865161 | % | Saimiri sciureus | |||
12. | ALA201782 | (-)-34a | F | = | 55 | % | ALA869999 | % | Canis lupus familiaris | |||
13. | ALA201782 | (-)-34a | F | = | 39 | % | ALA867017 | % | Rattus norvegicus | |||
14. | ALA201782 | (-)-34a | IC50 | = | 16 | nM | ALA859585 | 7.80 | nM | Oryctolagus cuniculus | ||
15. | ALA201782 | (-)-34a | CL | = | 17 | ml/min.kg | ALA859586 | mL.min-1.kg-1 | Saimiri sciureus | |||
16. | ALA201782 | (-)-34a | T1/2 | = | 8.8 | hr | ALA859584 | hr | Saimiri sciureus | |||
17. | ALA201782 | (-)-34a | CL | = | 3.6 | ml/min.kg | ALA859583 | mL.min-1.kg-1 | Canis lupus familiaris | |||
18. | ALA201782 | (-)-34a | T1/2 | = | 15 | hr | ALA859620 | hr | Canis lupus familiaris | |||
19. | ALA201782 | (-)-34a | IC50 | = | 0.32 | nM | ALA858799 | 9.49 | nM | Oryctolagus cuniculus | ||
20. | ALA201782 | (-)-34a | CL | = | 8.7 | ml/min.kg | ALA864080 | mL.min-1.kg-1 | Rattus norvegicus |