| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA383706 | 22a | pKa | = | 8.5 | ALA1012280 | ||||||
| 2. | ALA383706 | 22a | Tmax | = | 2 | hr | ALA1012279 | hr | Canis lupus familiaris | |||
| 3. | ALA383706 | 22a | F | = | 66 | % | ALA1012266 | % | Canis lupus familiaris | |||
| 4. | ALA383706 | 22a | t1/2 | = | 7 | hr | ALA1012278 | hr | Canis lupus familiaris | |||
| 5. | ALA383706 | 22a | Vdu | = | 1050 | L/Kg | ALA1012277 | L.kg-1 | Canis lupus familiaris | |||
| 6. | ALA383706 | 22a | Vd | = | 19 | L/Kg | ALA1012276 | L.kg-1 | Canis lupus familiaris | |||
| 7. | ALA383706 | 22a | CL | = | 31 | ml/min.kg | ALA1012275 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 8. | ALA383706 | 22a | logD | = | 2.3 | ALA1012274 | ||||||
| 9. | ALA383706 | 22a | Selectivity ratio | = | 770 | ALA1012273 | ||||||
| 10. | ALA383706 | 22a | Selectivity ratio | = | 90 | ALA1012272 | ||||||
| 11. | ALA383706 | 22a | IC50 | = | 770 | nM | ALA1012269 | 6.11 | nM | Homo sapiens | ||
| 12. | ALA383706 | 22a | IC50 | = | 90 | nM | ALA1012268 | 7.05 | nM | Homo sapiens | ||
| 13. | ALA383706 | 22a | IC50 | = | 1 | nM | ALA1012267 | 9.00 | nM | Homo sapiens | ||
| 14. | ALA383706 | 22a | permeability | = | 7 | %/hr | ALA1012271 | %/hr | Homo sapiens | |||
| 15. | ALA383706 | 22a | permeability | = | 18 | %/hr | ALA1012270 | %/hr | Homo sapiens | |||
| 16. | ALA383706 | 22a | Tmax | = | 1 | hr | ALA861237 | hr | Rattus norvegicus | |||
| 17. | ALA383706 | 22a | F | = | 44 | % | ALA861235 | % | Rattus norvegicus | |||
| 18. | ALA383706 | 22a | T1/2 | = | 4 | hr | ALA861233 | hr | Rattus norvegicus | |||
| 19. | ALA383706 | 22a | Vdss | = | 600 | L/kg | ALA861231 | L.kg-1 | Rattus norvegicus | |||
| 20. | ALA383706 | 22a | Vdss | = | 19 | L/kg | ALA861188 | L.kg-1 | Rattus norvegicus |
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