# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA383687 | 2v | F | = | 8.6 | % | ALA860626 | % | Rattus norvegicus | |||
2. | ALA383687 | 2v | Vss | = | 500 | ml/kg | ALA860625 | L.kg-1 | Rattus norvegicus | |||
3. | ALA383687 | 2v | CL | = | 18 | ml/min.kg | ALA860624 | mL.min-1.kg-1 | Rattus norvegicus | |||
4. | ALA383687 | 2v | T1/2 | = | 36 | min | ALA860623 | hr | Rattus norvegicus | |||
5. | ALA383687 | 2v | Solubility | = | 0.068 | mg/ml | ALA860622 | ug.mL-1 | ||||
6. | ALA383687 | 2v | Papp | = | 480 | nm/s | ALA860621 | nm/s | Canis lupus familiaris | |||
7. | ALA383687 | 2v | Ratio IC50 | = | 11 | ALA860620 | Homo sapiens | |||||
8. | ALA383687 | 2v | Ratio IC50 | = | 3.2 | ALA860619 | Homo sapiens | |||||
9. | ALA383687 | 2v | Ratio IC50 | = | 130 | ALA860758 | Homo sapiens | |||||
10. | ALA383687 | 2v | Ratio IC50 | > | 1400 | ALA866591 | Homo sapiens | |||||
11. | ALA383687 | 2v | Ratio IC50 | = | 360 | ALA866590 | Homo sapiens | |||||
12. | ALA383687 | 2v | Ratio IC50 | = | 79 | ALA866589 | ||||||
13. | ALA383687 | 2v | IC50 | = | 8.9 | nM | ALA866588 | 8.05 | nM | Homo sapiens |