# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA381394 | 2x | F | = | 8.8 | % | ALA860626 | % | Rattus norvegicus | |||
2. | ALA381394 | 2x | Vss | = | 1400 | ml/kg | ALA860625 | L.kg-1 | Rattus norvegicus | |||
3. | ALA381394 | 2x | CL | = | 83 | ml/min.kg | ALA860624 | mL.min-1.kg-1 | Rattus norvegicus | |||
4. | ALA381394 | 2x | T1/2 | = | 35 | min | ALA860623 | hr | Rattus norvegicus | |||
5. | ALA381394 | 2x | Solubility | = | 0.32 | mg/ml | ALA860622 | ug.mL-1 | ||||
6. | ALA381394 | 2x | Papp | = | 12 | nm/s | ALA860621 | nm/s | Canis lupus familiaris | |||
7. | ALA381394 | 2x | Ratio IC50 | = | 9.1 | ALA860620 | Homo sapiens | |||||
8. | ALA381394 | 2x | Ratio IC50 | = | 2.6 | ALA860619 | Homo sapiens | |||||
9. | ALA381394 | 2x | Ratio IC50 | = | 39 | ALA860758 | Homo sapiens | |||||
10. | ALA381394 | 2x | Ratio IC50 | > | 810 | ALA866591 | Homo sapiens | |||||
11. | ALA381394 | 2x | Ratio IC50 | = | 270 | ALA866590 | Homo sapiens | |||||
12. | ALA381394 | 2x | Ratio IC50 | = | 42 | ALA866589 | ||||||
13. | ALA381394 | 2x | IC50 | = | 15 | nM | ALA866588 | 7.82 | nM | Homo sapiens |