# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA377028 | 36 | Emax | = | 13 | % | ALA863074 | % | Homo sapiens | |||
2. | ALA377028 | 36 | Emax | = | 10 | % | ALA863073 | % | Homo sapiens | |||
3. | ALA377028 | 36 | Emax | = | 102 | % | ALA863070 | % | Homo sapiens | |||
4. | ALA377028 | 36 | Activity | = | 3 | ng/ml | ALA861645 | ng/ml | Mus musculus | |||
5. | ALA377028 | 36 | Activity | = | 6.7 | ng/ml | ALA861644 | ng/ml | Mus musculus | |||
6. | ALA377028 | 36 | Activity | = | 13.7 | ng/ml | ALA861643 | ng/ml | Mus musculus | |||
7. | ALA377028 | 36 | Activity | = | 5.4 | % | ALA861636 | % | Mus musculus | |||
8. | ALA377028 | 36 | Activity | = | 5.7 | % | ALA861672 | % | Mus musculus | |||
9. | ALA377028 | 36 | Activity | = | 7.2 | % | ALA861516 | % | Mus musculus | |||
10. | ALA377028 | 36 | Activity | = | 222 | mg Kg-1 | ALA861509 | mg Kg-1 | Mus musculus | |||
11. | ALA377028 | 36 | Activity | = | 238 | mg Kg-1 | ALA861508 | mg Kg-1 | Mus musculus | |||
12. | ALA377028 | 36 | Activity | = | 417 | mg Kg-1 | ALA861507 | mg Kg-1 | Mus musculus | |||
13. | ALA377028 | 36 | F | = | 40 | % | ALA861506 | % | Canis lupus familiaris | |||
14. | ALA377028 | 36 | T1/2 | = | 2.4 | hr | ALA861505 | hr | Canis lupus familiaris | |||
15. | ALA377028 | 36 | Vss | = | 0.37 | L/Kg | ALA860487 | L.kg-1 | Canis lupus familiaris | |||
16. | ALA377028 | 36 | CL | = | 11.3 | ml/min.Kg | ALA862151 | mL.min-1.kg-1 | Canis lupus familiaris | |||
17. | ALA377028 | 36 | AUC | = | 310 | ng.hr/ml | ALA862148 | ng.hr.mL-1 | Canis lupus familiaris | |||
18. | ALA377028 | 36 | Ratio EC50 | = | 2512 | ALA862150 | Homo sapiens | |||||
19. | ALA377028 | 36 | Log EC50 | = | -6.2 | ALA862149 | 6.20 | nM | Homo sapiens | |||
20. | ALA377028 | 36 | Ratio EC50 | = | 3981 | ALA862147 | Homo sapiens |