Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA211564	23d	BPR	=	0.17		ALA901342
2.	ALA211564	23d	Drug uptake	=	33	ng/g	ALA901341			ng/g	Mus musculus
3.	ALA211564	23d	F	=	11.2	%	ALA901340			%	Mus musculus
4.	ALA211564	23d	AUC	=	687	ng/mL.hr	ALA901339			ng.hr.mL-1	Mus musculus
5.	ALA211564	23d	Cmax	=	115	ng/ml	ALA901338		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Mus musculus
6.	ALA211564	23d	Tmax	=	2	hr	ALA901337			hr	Mus musculus
7.	ALA211564	23d	BPR	=	0.08		ALA901336
8.	ALA211564	23d	Drug uptake	=	43	ng/g	ALA901335			ng/g	Mus musculus
9.	ALA211564	23d	t1/2	=	3.8	hr	ALA901334			hr	Mus musculus
10.	ALA211564	23d	Vd	=	8.8	L/Kg	ALA901333			L.kg-1	Mus musculus
11.	ALA211564	23d	CL	=	26.9	ml/min.Kg	ALA900292			mL.min-1.kg-1	Mus musculus
12.	ALA211564	23d	Log D	=	4.5		ALA900288
13.	ALA211564	23d	IC50	=	1300	nM	ALA900286	5.89		nM	Homo sapiens
14.	ALA211564	23d	Ki	=	500	nM	ALA900285	6.30		nM	Homo sapiens
15.	ALA211564	23d	Ki	=	1200	nM	ALA900283	5.92		nM	Homo sapiens
16.	ALA211564	23d	Activity	=	18	%	ALA900287			%	Homo sapiens
17.	ALA211564	23d	Ki	=	19	nM	ALA900284	7.72		nM	Homo sapiens
18.	ALA211564	23d	Selectivity ratio	>	25		ALA913233				Homo sapiens
19.	ALA211564	23d	Ki	=	19	nM	ALA869276	7.72		nM	Homo sapiens
20.	ALA211564	23d	Inhibition	=	18	%	ALA869277			%	Homo sapiens