# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA386292 | 12ag | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA386292 | 12ag | IC50 | = | 5 | uM | ALA1260648 | 5.30 | nM | Mus musculus | ||
3. | ALA386292 | 12ag | Selectivity ratio | = | 4.3 | ALA1260647 | ||||||
4. | ALA386292 | 12ag | IC50 | = | 7300 | nM | ALA1260645 | 5.14 | nM | Homo sapiens | ||
5. | ALA386292 | 12ag | IC50 | = | 1700 | nM | ALA1260646 | 5.77 | nM | Homo sapiens | ||
6. | ALA386292 | 12ag | Selectivity ratio | = | 3.7 | ALA910295 | Plasmodium falciparum | |||||
7. | ALA386292 | 12ag | T1/2 | = | 3 | min | ALA910297 | hr | Mus musculus | |||
8. | ALA386292 | 12ag | Papp | = | 1.1 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
9. | ALA386292 | 12ag | IC50 | = | 880 | nM | ALA910294 | 6.06 | nM | Rattus norvegicus | ||
10. | ALA386292 | 12ag | IC50 | = | 240 | nM | ALA910293 | 6.62 | nM | Plasmodium falciparum | ||
11. | ALA386292 | 12ag | ED50 | = | 2500 | nM | ALA910292 | 5.60 | nM | Plasmodium falciparum | ||
12. | ALA386292 | 12ag | ED50 | = | 700 | nM | ALA910874 | 6.16 | nM | Plasmodium falciparum | ||
13. | ALA386292 | 12ag | Inhibition | = | 10 | % | ALA910873 | % | Plasmodium falciparum | |||
14. | ALA386292 | 12ag | Inhibition | = | 19 | % | ALA909787 | % | Plasmodium falciparum |