# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA379766 | 12q | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA379766 | 12q | IC50 | = | 0.1 | uM | ALA1260648 | 7.00 | nM | Mus musculus | ||
3. | ALA379766 | 12q | Selectivity ratio | = | 8.8 | ALA1260647 | ||||||
4. | ALA379766 | 12q | IC50 | = | 530 | nM | ALA1260645 | 6.28 | nM | Homo sapiens | ||
5. | ALA379766 | 12q | IC50 | = | 60 | nM | ALA1260646 | 7.22 | nM | Homo sapiens | ||
6. | ALA379766 | 12q | T1/2 | = | 4 | min | ALA910298 | hr | Rattus norvegicus | |||
7. | ALA379766 | 12q | T1/2 | < | 5 | min | ALA910297 | hr | Mus musculus | |||
8. | ALA379766 | 12q | Papp | = | 1.5 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
9. | ALA379766 | 12q | Selectivity ratio | = | 1.7 | ALA910295 | Plasmodium falciparum | |||||
10. | ALA379766 | 12q | IC50 | = | 7.5 | nM | ALA910294 | 8.12 | nM | Rattus norvegicus | ||
11. | ALA379766 | 12q | IC50 | = | 4.5 | nM | ALA910293 | 8.35 | nM | Plasmodium falciparum | ||
12. | ALA379766 | 12q | ED50 | = | 850 | nM | ALA910292 | 6.07 | nM | Plasmodium falciparum | ||
13. | ALA379766 | 12q | ED50 | = | 220 | nM | ALA910874 | 6.66 | nM | Plasmodium falciparum | ||
14. | ALA379766 | 12q | Inhibition | = | 63 | % | ALA910873 | % | Plasmodium falciparum | |||
15. | ALA379766 | 12q | Inhibition | = | 93 | % | ALA909787 | % | Plasmodium falciparum |