# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA214605 | 12ai | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA214605 | 12ai | IC50 | = | 4 | uM | ALA1260648 | 5.40 | nM | Mus musculus | ||
3. | ALA214605 | 12ai | Selectivity ratio | = | 15 | ALA1260647 | ||||||
4. | ALA214605 | 12ai | IC50 | = | 5800 | nM | ALA1260645 | 5.24 | nM | Homo sapiens | ||
5. | ALA214605 | 12ai | IC50 | = | 390 | nM | ALA1260646 | 6.41 | nM | Homo sapiens | ||
6. | ALA214605 | 12ai | T1/2 | = | 3.6 | min | ALA910297 | hr | Mus musculus | |||
7. | ALA214605 | 12ai | Papp | = | 1.1 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
8. | ALA214605 | 12ai | ED50 | = | 410 | nM | ALA910292 | 6.39 | nM | Plasmodium falciparum | ||
9. | ALA214605 | 12ai | ED50 | = | 257 | nM | ALA910874 | 6.59 | nM | Plasmodium falciparum | ||
10. | ALA214605 | 12ai | Inhibition | = | 39 | % | ALA910873 | % | Plasmodium falciparum | |||
11. | ALA214605 | 12ai | Inhibition | = | 85 | % | ALA909787 | % | Plasmodium falciparum |