# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA215780 | 12ae | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA215780 | 12ae | IC50 | > | 10 | uM | ALA1260648 | nM | Mus musculus | |||
3. | ALA215780 | 12ae | Selectivity ratio | = | 18 | ALA1260647 | ||||||
4. | ALA215780 | 12ae | IC50 | = | 6500 | nM | ALA1260645 | 5.19 | nM | Homo sapiens | ||
5. | ALA215780 | 12ae | IC50 | = | 370 | nM | ALA1260646 | 6.43 | nM | Homo sapiens | ||
6. | ALA215780 | 12ae | Selectivity ratio | = | 3.7 | ALA910295 | Plasmodium falciparum | |||||
7. | ALA215780 | 12ae | IC50 | = | 350 | nM | ALA910294 | 6.46 | nM | Rattus norvegicus | ||
8. | ALA215780 | 12ae | IC50 | = | 95 | nM | ALA910293 | 7.02 | nM | Plasmodium falciparum | ||
9. | ALA215780 | 12ae | ED50 | = | 4100 | nM | ALA910292 | 5.39 | nM | Plasmodium falciparum | ||
10. | ALA215780 | 12ae | ED50 | = | 1600 | nM | ALA910874 | 5.80 | nM | Plasmodium falciparum | ||
11. | ALA215780 | 12ae | Inhibition | = | 24 | % | ALA910873 | % | Plasmodium falciparum | |||
12. | ALA215780 | 12ae | Inhibition | = | 48 | % | ALA909787 | % | Plasmodium falciparum |