# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA385072 | 12v | IC50 | > | 2 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA385072 | 12v | IC50 | > | 2 | uM | ALA1260648 | nM | Mus musculus | |||
3. | ALA385072 | 12v | Selectivity ratio | > | 2.7 | ALA1260647 | ||||||
4. | ALA385072 | 12v | IC50 | > | 10000 | nM | ALA1260645 | nM | Homo sapiens | |||
5. | ALA385072 | 12v | IC50 | = | 3700 | nM | ALA1260646 | 5.43 | nM | Homo sapiens | ||
6. | ALA385072 | 12v | Selectivity ratio | = | 117 | ALA1000389 | ||||||
7. | ALA385072 | 12v | IC50 | = | 140 | nM | ALA1000388 | 6.85 | nM | |||
8. | ALA385072 | 12v | IC50 | = | 1.2 | nM | ALA1000383 | 8.92 | nM | |||
9. | ALA385072 | 12v | ED50 | = | 54 | nM | ALA1000387 | 7.27 | nM | Plasmodium falciparum | ||
10. | ALA385072 | 12v | ED50 | = | 88 | nM | ALA1000386 | 7.06 | nM | Plasmodium falciparum | ||
11. | ALA385072 | 12v | INH | = | 81 | % | ALA1000385 | % | ||||
12. | ALA385072 | 12v | INH | = | 96 | % | ALA1000384 | % | ||||
13. | ALA385072 | 12v | beta t1/2 | = | 70 | min | ALA910301 | hr | Mus musculus | |||
14. | ALA385072 | 12v | Cmax | = | 2.97 | uM | ALA910300 | nM | Mus musculus | |||
15. | ALA385072 | 12v | AUC | = | 414 | uM.min | ALA910299 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
16. | ALA385072 | 12v | T1/2 | = | 60 | min | ALA910298 | hr | Rattus norvegicus | |||
17. | ALA385072 | 12v | T1/2 | = | 14 | min | ALA910297 | hr | Mus musculus | |||
18. | ALA385072 | 12v | Papp | = | 0.9 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
19. | ALA385072 | 12v | ED50 | = | 54 | nM | ALA910292 | 7.27 | nM | Plasmodium falciparum | ||
20. | ALA385072 | 12v | ED50 | = | 88 | nM | ALA910874 | 7.06 | nM | Plasmodium falciparum |