# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA384373 | 12e | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA384373 | 12e | IC50 | = | 0.3 | uM | ALA1260648 | 6.52 | nM | Mus musculus | ||
3. | ALA384373 | 12e | Selectivity ratio | = | 7.6 | ALA1260647 | ||||||
4. | ALA384373 | 12e | IC50 | = | 310 | nM | ALA1260645 | 6.51 | nM | Homo sapiens | ||
5. | ALA384373 | 12e | IC50 | = | 41 | nM | ALA1260646 | 7.39 | nM | Homo sapiens | ||
6. | ALA384373 | 12e | Selectivity ratio | = | 1.5 | ALA910295 | Plasmodium falciparum | |||||
7. | ALA384373 | 12e | IC50 | = | 13 | nM | ALA910294 | 7.89 | nM | Rattus norvegicus | ||
8. | ALA384373 | 12e | IC50 | = | 8.9 | nM | ALA910293 | 8.05 | nM | Plasmodium falciparum | ||
9. | ALA384373 | 12e | ED50 | = | 2250 | nM | ALA910292 | 5.65 | nM | Plasmodium falciparum | ||
10. | ALA384373 | 12e | ED50 | = | 2500 | nM | ALA910874 | 5.60 | nM | Plasmodium falciparum | ||
11. | ALA384373 | 12e | Inhibition | = | 18 | % | ALA910873 | % | Plasmodium falciparum | |||
12. | ALA384373 | 12e | Inhibition | = | 69 | % | ALA909787 | % | Plasmodium falciparum |