# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA215476 | 12g | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA215476 | 12g | IC50 | = | 0.09 | uM | ALA1260648 | 7.05 | nM | Mus musculus | ||
3. | ALA215476 | 12g | Selectivity ratio | = | 113 | ALA1260647 | ||||||
4. | ALA215476 | 12g | IC50 | = | 820 | nM | ALA1260645 | 6.09 | nM | Homo sapiens | ||
5. | ALA215476 | 12g | IC50 | = | 25 | nM | ALA1260646 | 7.60 | nM | Homo sapiens | ||
6. | ALA215476 | 12g | Tmax | = | 30 | min | ALA910305 | hr | Mus musculus | |||
7. | ALA215476 | 12g | beta t1/2 | = | 15.6 | min | ALA910301 | hr | Mus musculus | |||
8. | ALA215476 | 12g | Cmax | = | 0.31 | uM | ALA910300 | nM | Mus musculus | |||
9. | ALA215476 | 12g | AUC | = | 20.9 | uM.min | ALA910299 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
10. | ALA215476 | 12g | T1/2 | = | 10.9 | min | ALA910298 | hr | Rattus norvegicus | |||
11. | ALA215476 | 12g | T1/2 | = | 21 | min | ALA910297 | hr | Mus musculus | |||
12. | ALA215476 | 12g | Papp | = | 2.8 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
13. | ALA215476 | 12g | ED50 | = | 2300 | nM | ALA910292 | 5.64 | nM | Plasmodium falciparum | ||
14. | ALA215476 | 12g | ED50 | = | 570 | nM | ALA910874 | 6.24 | nM | Plasmodium falciparum | ||
15. | ALA215476 | 12g | Inhibition | = | 64 | % | ALA910873 | % | Plasmodium falciparum | |||
16. | ALA215476 | 12g | Inhibition | = | 95 | % | ALA909787 | % | Plasmodium falciparum |