# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA384161 | 12w | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA384161 | 12w | IC50 | > | 10 | uM | ALA1260648 | nM | Mus musculus | |||
3. | ALA384161 | 12w | Selectivity ratio | > | 20 | ALA1260647 | ||||||
4. | ALA384161 | 12w | IC50 | > | 10000 | nM | ALA1260645 | nM | Homo sapiens | |||
5. | ALA384161 | 12w | IC50 | = | 510 | nM | ALA1260646 | 6.29 | nM | Homo sapiens | ||
6. | ALA384161 | 12w | ED50 | = | 85 | nM | ALA1000387 | 7.07 | nM | Plasmodium falciparum | ||
7. | ALA384161 | 12w | ED50 | = | 130 | nM | ALA1000386 | 6.89 | nM | Plasmodium falciparum | ||
8. | ALA384161 | 12w | INH | = | 74 | % | ALA1000385 | % | ||||
9. | ALA384161 | 12w | INH | = | 96 | % | ALA1000384 | % | ||||
10. | ALA384161 | 12w | T1/2 | = | 40 | min | ALA910298 | hr | Rattus norvegicus | |||
11. | ALA384161 | 12w | T1/2 | = | 17 | min | ALA910297 | hr | Mus musculus | |||
12. | ALA384161 | 12w | Papp | = | 1.1 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
13. | ALA384161 | 12w | ED50 | = | 85 | nM | ALA910292 | 7.07 | nM | Plasmodium falciparum | ||
14. | ALA384161 | 12w | ED50 | = | 130 | nM | ALA910874 | 6.89 | nM | Plasmodium falciparum | ||
15. | ALA384161 | 12w | Inhibition | = | 74 | % | ALA910873 | % | Plasmodium falciparum | |||
16. | ALA384161 | 12w | Inhibition | = | 96 | % | ALA909787 | % | Plasmodium falciparum |