# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA215083 | 12b | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA215083 | 12b | IC50 | = | 1.6 | uM | ALA1260648 | 5.80 | nM | Mus musculus | ||
3. | ALA215083 | 12b | Selectivity ratio | = | 6.7 | ALA1260647 | ||||||
4. | ALA215083 | 12b | IC50 | = | 530 | nM | ALA1260645 | 6.28 | nM | Homo sapiens | ||
5. | ALA215083 | 12b | IC50 | = | 79 | nM | ALA1260646 | 7.10 | nM | Homo sapiens | ||
6. | ALA215083 | 12b | T1/2 | = | 2.9 | min | ALA910297 | hr | Mus musculus | |||
7. | ALA215083 | 12b | Selectivity ratio | = | 145 | ALA910295 | Plasmodium falciparum | |||||
8. | ALA215083 | 12b | IC50 | = | 290 | nM | ALA910294 | 6.54 | nM | Rattus norvegicus | ||
9. | ALA215083 | 12b | IC50 | = | 2 | nM | ALA910293 | 8.70 | nM | Plasmodium falciparum | ||
10. | ALA215083 | 12b | ED50 | = | 3200 | nM | ALA910292 | 5.50 | nM | Plasmodium falciparum | ||
11. | ALA215083 | 12b | ED50 | = | 675 | nM | ALA910874 | 6.17 | nM | Plasmodium falciparum | ||
12. | ALA215083 | 12b | Inhibition | = | 70 | % | ALA910873 | % | Plasmodium falciparum | |||
13. | ALA215083 | 12b | Inhibition | = | 95 | % | ALA909787 | % | Plasmodium falciparum |