# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA214610 | 12x | IC50 | > | 10 | uM | ALA1260649 | nM | Mus musculus | |||
2. | ALA214610 | 12x | IC50 | = | 1 | uM | ALA1260648 | 6.00 | nM | Mus musculus | ||
3. | ALA214610 | 12x | Selectivity ratio | = | 15 | ALA1260647 | ||||||
4. | ALA214610 | 12x | IC50 | = | 780 | nM | ALA1260645 | 6.11 | nM | Homo sapiens | ||
5. | ALA214610 | 12x | IC50 | = | 51 | nM | ALA1260646 | 7.29 | nM | Homo sapiens | ||
6. | ALA214610 | 12x | ED50 | = | 150 | nM | ALA1000387 | 6.82 | nM | Plasmodium falciparum | ||
7. | ALA214610 | 12x | ED50 | = | 93 | nM | ALA1000386 | 7.03 | nM | Plasmodium falciparum | ||
8. | ALA214610 | 12x | INH | = | 95 | % | ALA1000385 | % | ||||
9. | ALA214610 | 12x | INH | = | 99 | % | ALA1000384 | % | ||||
10. | ALA214610 | 12x | Tmax | = | 40 | min | ALA910305 | hr | Mus musculus | |||
11. | ALA214610 | 12x | beta t1/2 | = | 32.6 | min | ALA910304 | hr | Rattus norvegicus | |||
12. | ALA214610 | 12x | Cmax | = | 1.05 | uM | ALA910303 | nM | Rattus norvegicus | |||
13. | ALA214610 | 12x | AUC | = | 103 | uM.min | ALA910302 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
14. | ALA214610 | 12x | T1/2 | = | 20 | min | ALA910298 | hr | Rattus norvegicus | |||
15. | ALA214610 | 12x | T1/2 | = | 8 | min | ALA910297 | hr | Mus musculus | |||
16. | ALA214610 | 12x | Papp | = | 0.4 | ucm/s | ALA910296 | ucm/s | Homo sapiens | |||
17. | ALA214610 | 12x | Selectivity ratio | = | 27 | ALA910295 | Plasmodium falciparum | |||||
18. | ALA214610 | 12x | IC50 | = | 15.5 | nM | ALA910294 | 7.81 | nM | Rattus norvegicus | ||
19. | ALA214610 | 12x | IC50 | = | 0.6 | nM | ALA910293 | 9.22 | nM | Plasmodium falciparum | ||
20. | ALA214610 | 12x | ED50 | = | 150 | nM | ALA910292 | 6.82 | nM | Plasmodium falciparum |