| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA437341 | 25, ABT-341 | Ki | = | 1.6 | nM | ALA856680 | 8.80 | nM | Homo sapiens | ||
| 2. | ALA437341 | 25, ABT-341 | Activity | 0 | ALA909956 | Active | Canis lupus familiaris | |||||
| 3. | ALA437341 | 25, ABT-341 | F | = | 54 | % | ALA856704 | % | Cercopithecidae | |||
| 4. | ALA437341 | 25, ABT-341 | Vss | = | 3.2 | L/Kg | ALA856703 | L.kg-1 | Cercopithecidae | |||
| 5. | ALA437341 | 25, ABT-341 | T1/2 | = | 6.3 | hr | ALA856702 | hr | Cercopithecidae | |||
| 6. | ALA437341 | 25, ABT-341 | T1/2 | = | 4.3 | hr | ALA856701 | hr | Cercopithecidae | |||
| 7. | ALA437341 | 25, ABT-341 | Tmax | = | 2.7 | hr | ALA856700 | hr | Cercopithecidae | |||
| 8. | ALA437341 | 25, ABT-341 | Cmax | = | 345 | ng/ml | ALA856699 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Cercopithecidae | ||
| 9. | ALA437341 | 25, ABT-341 | AUC | = | 1905 | ng.hr/g | ALA856698 | ng.hr/g | Cercopithecidae | |||
| 10. | ALA437341 | 25, ABT-341 | AUC | = | 3557 | ng.hr/g | ALA856697 | ng.hr/g | Cercopithecidae | |||
| 11. | ALA437341 | 25, ABT-341 | F | = | 104 | % | ALA856696 | % | Canis lupus familiaris | |||
| 12. | ALA437341 | 25, ABT-341 | Vss | = | 4.03 | L/Kg | ALA856695 | L.kg-1 | Canis lupus familiaris | |||
| 13. | ALA437341 | 25, ABT-341 | T1/2 | = | 6.7 | hr | ALA856694 | hr | Canis lupus familiaris | |||
| 14. | ALA437341 | 25, ABT-341 | T1/2 | = | 7 | hr | ALA856693 | hr | Canis lupus familiaris | |||
| 15. | ALA437341 | 25, ABT-341 | Tmax | = | 0.58 | hr | ALA856692 | hr | Canis lupus familiaris | |||
| 16. | ALA437341 | 25, ABT-341 | Cmax | = | 718 | ng/ml | ALA856691 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 17. | ALA437341 | 25, ABT-341 | AUC | = | 6285 | ng.hr/g | ALA856690 | ng.hr/g | Canis lupus familiaris | |||
| 18. | ALA437341 | 25, ABT-341 | AUC | = | 6019 | ng.hr/g | ALA856689 | ng.hr/g | Canis lupus familiaris | |||
| 19. | ALA437341 | 25, ABT-341 | F | = | 67 | % | ALA856688 | % | Rattus norvegicus | |||
| 20. | ALA437341 | 25, ABT-341 | Vss | = | 7.19 | L/Kg | ALA856687 | L.kg-1 | Rattus norvegicus |
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