# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA386974 | 29, BG9928 | ED50 | = | 15 | ug/kg | ALA910013 | mg.kg-1 | Rattus norvegicus | |||
2. | ALA386974 | 29, BG9928 | pA2 | = | 9.8 | ALA910630 | 9.80 | nM | Rattus norvegicus | |||
3. | ALA386974 | 29, BG9928 | ED50 | = | 15 | ug/kg | ALA910629 | mg.kg-1 | Rattus norvegicus | |||
4. | ALA386974 | 29, BG9928 | EC50 | = | 16.1 | nM | ALA910630 | 7.79 | nM | Rattus norvegicus | ||
5. | ALA386974 | 29, BG9928 | Solubility | = | 12.4 | mg/ml | ALA910032 | ug.mL-1 | ||||
6. | ALA386974 | 29, BG9928 | Solubility | = | 25.4 | mg/ml | ALA910031 | ug.mL-1 | ||||
7. | ALA386974 | 29, BG9928 | Solubility | = | 24.4 | mg/ml | ALA910030 | ug.mL-1 | ||||
8. | ALA386974 | 29, BG9928 | Vdss | = | 4.25 | L/Kg | ALA910029 | L.kg-1 | Macaca fascicularis | |||
9. | ALA386974 | 29, BG9928 | Vdss | = | 2.64 | L/Kg | ALA910028 | L.kg-1 | Canis lupus familiaris | |||
10. | ALA386974 | 29, BG9928 | Vdss | = | 0.32 | L/Kg | ALA910027 | L.kg-1 | Rattus norvegicus | |||
11. | ALA386974 | 29, BG9928 | CL | = | 5.82 | ml/min.kg | ALA910025 | mL.min-1.kg-1 | Macaca fascicularis | |||
12. | ALA386974 | 29, BG9928 | CL | = | 11.8 | ml/min.kg | ALA910024 | mL.min-1.kg-1 | Canis lupus familiaris | |||
13. | ALA386974 | 29, BG9928 | CL | = | 1.56 | ml/min.kg | ALA910023 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA386974 | 29, BG9928 | T1/2 | = | 11.1 | hr | ALA910021 | hr | Macaca fascicularis | |||
15. | ALA386974 | 29, BG9928 | T1/2 | = | 6.4 | hr | ALA910020 | hr | Canis lupus familiaris | |||
16. | ALA386974 | 29, BG9928 | T1/2 | = | 3.14 | hr | ALA910019 | hr | Rattus norvegicus | |||
17. | ALA386974 | 29, BG9928 | F | = | 94 | % | ALA910017 | % | Macaca fascicularis | |||
18. | ALA386974 | 29, BG9928 | F | = | 78 | % | ALA910016 | % | Canis lupus familiaris | |||
19. | ALA386974 | 29, BG9928 | F | = | 99 | % | ALA910015 | % | Rattus norvegicus | |||
20. | ALA386974 | 29, BG9928 | Ki | = | 2440 | nM | ALA910011 | 5.61 | nM | Rattus norvegicus |