| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA214585 | 12 | IC50 | > | 10 | uM | ALA907673 | nM | Homo sapiens | |||
| 2. | ALA214585 | 12 | IC50 | = | 0.015 | uM | ALA907673 | 7.82 | nM | Homo sapiens | ||
| 3. | ALA214585 | 12 | IC50 | = | 0.036 | uM | ALA907673 | 7.44 | nM | Homo sapiens | ||
| 4. | ALA214585 | 12 | IC50 | > | 10 | uM | ALA907669 | nM | Homo sapiens | |||
| 5. | ALA214585 | 12 | IC50 | > | 10 | uM | ALA907668 | nM | Homo sapiens | |||
| 6. | ALA214585 | 12 | Weight loss | = | 7 | % | ALA856580 | p<0.01 | % | Mus musculus | ||
| 7. | ALA214585 | 12 | Brain conc | = | 0 | ng/g | ALA856579 | ng/g | Mus musculus | |||
| 8. | ALA214585 | 12 | Brain conc | = | 530 | ng/g | ALA856578 | ng/g | Mus musculus | |||
| 9. | ALA214585 | 12 | Plasma conc | = | 203 | ng/ml | ALA856577 | ng/ml | Mus musculus | |||
| 10. | ALA214585 | 12 | Plasma conc | = | 3680 | ng/ml | ALA856576 | ng/ml | Mus musculus | |||
| 11. | ALA214585 | 12 | T1/2 | = | 4.1 | h | ALA856575 | hr | Mus musculus | |||
| 12. | ALA214585 | 12 | T1/2 | = | 5.7 | h | ALA856575 | hr | Mus musculus | |||
| 13. | ALA214585 | 12 | Cmax | = | 1.43 | ug/g | ALA856574 | ug/g | Mus musculus | |||
| 14. | ALA214585 | 12 | Cmax | = | 0.686 | ug/g | ALA856574 | ug/g | Mus musculus | |||
| 15. | ALA214585 | 12 | AUC | = | 8.26 | ug h/g | ALA856573 | ug h/g | Mus musculus | |||
| 16. | ALA214585 | 12 | AUC | = | 4.85 | ug h/g | ALA856573 | ug h/g | Mus musculus | |||
| 17. | ALA214585 | 12 | T1/2 | = | 3.6 | h | ALA856572 | hr | Mus musculus | |||
| 18. | ALA214585 | 12 | T1/2 | = | 4.5 | h | ALA856572 | hr | Mus musculus | |||
| 19. | ALA214585 | 12 | Cmax | = | 15.5 | ug/ml | ALA856571 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 20. | ALA214585 | 12 | Cmax | = | 15 | ug/ml | ALA856571 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus |
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