Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA373882	63	Solubility	=	0.044	mg/ml	ALA910165		ug.mL-1
2.	ALA373882	63	Solubility	=	0.34	mg/ml	ALA910164		ug.mL-1
3.	ALA373882	63	Solubility	=	1.32	mg/ml	ALA910163		ug.mL-1
4.	ALA373882	63	pKa	=	9.5		ALA910162
5.	ALA373882	63	Tmax	=	2	hr	ALA910161		hr	Rattus norvegicus
6.	ALA373882	63	Cp	=	1593.12	nM	ALA910159		nM	Mus musculus
7.	ALA373882	63	Cp	=	3033.69	nM	ALA910158		nM	Mus musculus
8.	ALA373882	63	Inhibition	=	25	%	ALA910157		%	Mus musculus
9.	ALA373882	63	Inhibition	=	94	%	ALA910156		%	Mus musculus
10.	ALA373882	63	Cp	=	3970.61	nM	ALA910155		nM	Mus musculus
11.	ALA373882	63	PPB	=	92.2	%	ALA910154		%	Rattus norvegicus
12.	ALA373882	63	PPB	=	98	%	ALA910153		%	Mus musculus
13.	ALA373882	63	PPB	=	93	%	ALA910152		%	Rattus norvegicus
14.	ALA373882	63	AUC	=	2640	ng.hr/ml	ALA910151		ng.hr.mL-1	Rattus norvegicus
15.	ALA373882	63	Cmax	=	520	ng/ml	ALA910150	standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
16.	ALA373882	63	F	=	31	%	ALA910149		%	Rattus norvegicus
17.	ALA373882	63	Vss	=	2560	ml/kg	ALA910148		L.kg-1	Rattus norvegicus
18.	ALA373882	63	CL	=	1300	ml/hr.kg	ALA910147		mL.min-1.kg-1	Rattus norvegicus
19.	ALA373882	63	t1/2	=	1.6	hr	ALA910146		hr	Rattus norvegicus
20.	ALA373882	63	Ratio IC50	>	250		ALA908507			Homo sapiens