# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA386637 | 6l | Fu | = | 32 | nM | ALA909600 | nM | Mus musculus | |||
2. | ALA386637 | 6l | F | = | 39 | % | ALA909599 | % | Rattus norvegicus | |||
3. | ALA386637 | 6l | AUC | = | 800 | ng.hr/ml | ALA909598 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA386637 | 6l | t1/2 | = | 7.9 | hr | ALA909597 | hr | Rattus norvegicus | |||
5. | ALA386637 | 6l | Vss | = | 11.8 | L/Kg | ALA909596 | L.kg-1 | Rattus norvegicus | |||
6. | ALA386637 | 6l | CL | = | 2.4 | L/hr.Kg | ALA909595 | mL.min-1.kg-1 | Rattus norvegicus | |||
7. | ALA386637 | 6l | CL | < | 50 | uL/min.mg | ALA909594 | mL.min-1.g-1 | ||||
8. | ALA386637 | 6l | CL | = | 677 | uL/min.mg | ALA910196 | mL.min-1.g-1 | Rattus norvegicus | |||
9. | ALA386637 | 6l | PPB | = | 97.9 | % | ALA910195 | % | Mus musculus | |||
10. | ALA386637 | 6l | Cp | = | 1660 | nM | ALA910194 | nM | Mus musculus | |||
11. | ALA386637 | 6l | Inhibition | = | 50 | % | ALA910193 | % | Mus musculus | |||
12. | ALA386637 | 6l | Activity | 0 | ALA910192 | Dose-dependent effect | Mus musculus | |||||
13. | ALA386637 | 6l | IC50 | > | 8300 | nM | ALA910191 | nM | Homo sapiens | |||
14. | ALA386637 | 6l | IC50 | > | 100000 | nM | ALA910190 | nM | Homo sapiens | |||
15. | ALA386637 | 6l | IC50 | > | 6700 | nM | ALA910189 | nM | Homo sapiens | |||
16. | ALA386637 | 6l | IC50 | = | 18 | nM | ALA910188 | 7.75 | nM | Homo sapiens | ||
17. | ALA386637 | 6l | IC50 | = | 2900 | nM | ALA910187 | 5.54 | nM | Homo sapiens | ||
18. | ALA386637 | 6l | IC50 | > | 5000 | nM | ALA910186 | nM | Homo sapiens | |||
19. | ALA386637 | 6l | IC50 | = | 2800 | nM | ALA910185 | 5.55 | nM | Homo sapiens | ||
20. | ALA386637 | 6l | IC50 | = | 290 | nM | ALA910184 | 6.54 | nM | Homo sapiens |