| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA221113 | 58 | Intrinsic activity | = | 0.5 | ALA918973 | Partial agonist | Homo sapiens | ||||
| 2. | ALA221113 | 58 | Intrinsic activity | = | 0.5 | ALA918972 | Partial agonist | Homo sapiens | ||||
| 3. | ALA221113 | 58 | BPR | > | 1 | ALA920401 | Rattus norvegicus | |||||
| 4. | ALA221113 | 58 | BPR | > | 1 | ALA920400 | Rattus norvegicus | |||||
| 5. | ALA221113 | 58 | BPR | > | 1 | ALA920399 | Rattus norvegicus | |||||
| 6. | ALA221113 | 58 | BPR | > | 1 | ALA920398 | Rattus norvegicus | |||||
| 7. | ALA221113 | 58 | Activity | 0 | ALA920397 | Not Evaluated | Mus musculus | |||||
| 8. | ALA221113 | 58 | Activity | = | 6.1 | % | ALA920396 | % | Rattus norvegicus | |||
| 9. | ALA221113 | 58 | Activity | = | 1.6 | % | ALA920395 | % | Rattus norvegicus | |||
| 10. | ALA221113 | 58 | Activity | = | 12 | % | ALA920391 | % | Rattus norvegicus | |||
| 11. | ALA221113 | 58 | Activity | = | 41 | % | ALA920390 | % | Rattus norvegicus | |||
| 12. | ALA221113 | 58 | Activity | = | 32 | % | ALA920389 | % | Rattus norvegicus | |||
| 13. | ALA221113 | 58 | IC50 | = | 8.7 | uM | ALA920388 | 5.06 | nM | Homo sapiens | ||
| 14. | ALA221113 | 58 | Fu | = | 17 | % | ALA920387 | Rattus norvegicus | ||||
| 15. | ALA221113 | 58 | Fu | = | 17 | % | ALA920386 | Homo sapiens | ||||
| 16. | ALA221113 | 58 | PPB | = | 83 | % | ALA920385 | % | Rattus norvegicus | |||
| 17. | ALA221113 | 58 | permeability | = | 212 | nm/s | ALA920384 | nm/s | Homo sapiens | |||
| 18. | ALA221113 | 58 | Vss | = | 4.8 | L/Kg | ALA920383 | L.kg-1 | Rattus norvegicus | |||
| 19. | ALA221113 | 58 | CL | = | 37.4 | ml/min.kg | ALA920382 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 20. | ALA221113 | 58 | F | = | 77 | % | ALA920381 | % | Rattus norvegicus |
The page will load shortly, Thanks for your patience!