# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA225085 | S-30 | F | = | 70 | % | ALA914059 | % | Rattus norvegicus | |||
2. | ALA225085 | S-30 | Fu | = | 0.083 | ALA914058 | ||||||
3. | ALA225085 | S-30 | t1/2 | = | 1.9 | hr | ALA914057 | hr | Rattus norvegicus | |||
4. | ALA225085 | S-30 | Vdss | = | 0.6 | L/Kg | ALA914056 | L.kg-1 | Rattus norvegicus | |||
5. | ALA225085 | S-30 | CL | = | 3.5 | ml/min.kg | ALA914055 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA225085 | S-30 | IC50 | = | 3.8 | nM | ALA914054 | 8.42 | nM | |||
7. | ALA225085 | S-30 | IC50 | = | 10.5 | nM | ALA914053 | 7.98 | nM | Homo sapiens | ||
8. | ALA225085 | S-30 | IC50 | = | 5.4 | nM | ALA914052 | 8.27 | nM | Homo sapiens | ||
9. | ALA225085 | S-30 | IC50 | = | 0.8 | nM | ALA914051 | 9.10 | nM | Oryctolagus cuniculus | ||
10. | ALA225085 | S-30 | IC50 | = | 0.6 | nM | ALA914050 | 9.22 | nM | Rattus norvegicus | ||
11. | ALA225085 | S-30 | IC50 | = | 2.3 | nM | ALA914049 | 8.64 | nM | Homo sapiens | ||
12. | ALA225085 | S-30 | Papp | = | 14 | ucm/s | ALA914048 | ucm/s | Homo sapiens | |||
13. | ALA225085 | S-30 | Papp | = | 12 | ucm/s | ALA914047 | ucm/s | Homo sapiens | |||
14. | ALA225085 | S-30 | t1/2 | > | 120 | min | ALA914046 | hr | Homo sapiens | |||
15. | ALA225085 | S-30 | PPB | = | 98.3 | % | ALA914045 | % | Rattus norvegicus | |||
16. | ALA225085 | S-30 | Log D | = | 1 | ALA914044 | ||||||
17. | ALA225085 | S-30 | Activity | > | 3 | uM | ALA914043 | uM | Homo sapiens | |||
18. | ALA225085 | S-30 | Activity | > | 3 | uM | ALA914042 | uM | ||||
19. | ALA225085 | S-30 | IC50 | = | 0.9 | nM | ALA914041 | 9.05 | nM |