# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1450 | 10 | IC50 | = | 5090 | nM | ALA5244559 | 5.29 | nM | Plasmodium falciparum | ||
2. | ALA1450 | 10 | IC50 | = | 0.3 | nM | ALA5244558 | 9.52 | nM | Plasmodium falciparum | ||
3. | ALA1450 | 10 | IC50 | = | 0.5 | nM | ALA5244557 | 9.30 | nM | Plasmodium falciparum | ||
4. | ALA1450 | 10 | IC50 | = | 2.4 | nM | ALA5232768 | 8.62 | nM | Toxoplasma gondii | ||
5. | ALA1450 | 10 | ED50 | = | 2.53 | mg/kg/day | ALA5232764 | mg/kg/day | Toxoplasma gondii | |||
6. | ALA1450 | 10 | EC50 | = | 0.032 | uM | ALA5232742 | 7.50 | nM | Toxoplasma gondii | ||
7. | ALA1450 | 10 | EC50 | = | 0.001 | uM | ALA5150534 | 9.00 | nM | Plasmodium falciparum | ||
8. | ALA1450 | 10 | Activity | 0 | ALA5150532 | Active | Plasmodium falciparum | |||||
9. | ALA1450 | 10 | Activity | 0 | ALA5150531 | Active | Plasmodium falciparum | |||||
10. | ALA1450 | 10 | CC50 | > | 30 | uM | ALA5150530 | nM | Homo sapiens | |||
11. | ALA1450 | 10 | EC50 | = | 0.001 | uM | ALA5150529 | 8.89 | nM | Plasmodium falciparum | ||
12. | ALA1450 | 10 | IC50 | = | 0.23 | uM | ALA5128698 | 6.64 | nM | Homo sapiens | ||
13. | ALA1450 | 10 | IC90 | 0 | ALA4429520 | Not Determined | Plasmodium falciparum | |||||
14. | ALA1450 | 10 | IC50 | > | 1000 | nM | ALA4429521 | nM | Plasmodium falciparum | |||
15. | ALA1450 | 10 | IC50 | = | 0.6 | nM | ALA4429519 | 9.22 | nM | Plasmodium falciparum | ||
16. | ALA1450 | 10 | EC50 | = | 28.3 | uM | ALA4426094 | 4.55 | nM | Mus musculus | ||
17. | ALA1450 | 10 | EC50 | = | 18.4 | uM | ALA4426092 | 4.74 | nM | Plasmodium falciparum | ||
18. | ALA1450 | 10 | EC50 | = | 1.39 | nM | ALA4426091 | 8.86 | nM | Plasmodium falciparum | ||
19. | ALA1450 | 10 | Time | = | 30 | day | ALA4426102 | hr | Plasmodium berghei | |||
20. | ALA1450 | 10 | INH | = | 99 | % | ALA4426101 | % | Plasmodium berghei |