| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  4-Aminopyrazolo[3,4-d]pyrimidine | 5 | Ratio CC50/IC50 | > | 355 | ALA4812136 | ||||||
| 2. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | CC50 | > | 64 | uM | ALA4812135 | nM | Mus musculus | |||
| 3. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | IC50 | = | 0.18 | uM | ALA4812134 | 6.75 | nM | Leishmania infantum | ||
| 4. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | Ratio CC50/IC50 | = | 5 | ALA4812133 | ||||||
| 5. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | CC50 | = | 2.46 | uM | ALA4812132 | nM | ||||
| 6. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | IC50 | = | 0.57 | uM | ALA4812131 | 6.24 | nM | Trypanosoma cruzi | ||
| 7. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | Ki | = | 11312 | nM | ALA5040108 | 4.95 | nM | Homo sapiens | ||
| 8. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | IC50 | = | 26630 | nM | ALA5040107 | 4.58 | nM | Homo sapiens | ||
| 9. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | Inhibition | = | 49.8 | % | ALA905369 | % | Homo sapiens | |||
| 10. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | IC50 | = | 30.26 | uM | ALA905368 | 4.52 | nM | Homo sapiens | ||
| 11. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | Ki | = | 99.9 | uM | ALA758630 | 4.00 | nM | Homo sapiens | ||
| 12. | 4-Aminopyrazolo[3,4-d]pyrimidine | 5 | IC50 | = | 144.9 | uM | ALA758627 | nM | Homo sapiens |
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