# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA387935 | 18 | Activity | 0 | ALA905127 | Not Active | Canis lupus familiaris | |||||
2. | ALA387935 | 18 | Activity | 0 | ALA905126 | Not Active | Canis lupus familiaris | |||||
3. | ALA387935 | 18 | F | = | 7 | % | ALA905124 | % | Rattus norvegicus | |||
4. | ALA387935 | 18 | CL | = | 48.5 | ml/min.kg | ALA905122 | mL.min-1.kg-1 | Rattus norvegicus | |||
5. | ALA387935 | 18 | Vdss | = | 19 | L/Kg | ALA905120 | L.kg-1 | Rattus norvegicus | |||
6. | ALA387935 | 18 | t1/2 | = | 4.5 | hr | ALA905118 | hr | Rattus norvegicus | |||
7. | ALA387935 | 18 | IC50 | = | 2.4 | uM | ALA905113 | 5.62 | nM | Rattus norvegicus | ||
8. | ALA387935 | 18 | IC50 | = | 11 | uM | ALA905112 | 4.96 | nM | Rattus norvegicus | ||
9. | ALA387935 | 18 | Activity | = | 10 | umol/Kg | ALA905117 | umol/Kg | Canis lupus familiaris | |||
10. | ALA387935 | 18 | Activity | 0 | ALA905116 | Active | Canis lupus familiaris | |||||
11. | ALA387935 | 18 | Activity | = | 17 | umol/Kg | ALA905115 | umol/Kg | Canis lupus familiaris | |||
12. | ALA387935 | 18 | Activity | 0 | ALA905114 | Active | Canis lupus familiaris | |||||
13. | ALA387935 | 18 | IC50 | = | 3.6 | uM | ALA905111 | 5.44 | nM | Homo sapiens | ||
14. | ALA387935 | 18 | IC50 | = | 15 | uM | ALA905110 | 4.82 | nM | Homo sapiens | ||
15. | ALA387935 | 18 | Activity | = | 1.7 | micromol/kg/min | ALA905108 | micromol/kg/min | Rattus norvegicus | |||
16. | ALA387935 | 18 | Activity | = | 6.4 | micromol/kg/min | ALA905107 | micromol/kg/min | Rattus norvegicus | |||
17. | ALA387935 | 18 | Activity | = | 1.4 | micromol/kg/min | ALA905106 | micromol/kg/min | Rattus norvegicus | |||
18. | ALA387935 | 18 | Activity | = | 1.4 | micromol/kg/min | ALA905105 | micromol/kg/min | Rattus norvegicus | |||
19. | ALA387935 | 18 | ED50 | = | 1.5 | micromol/kg/min | ALA904109 | micromol/kg/min | Rattus norvegicus | |||
20. | ALA387935 | 18 | LD50 | = | 228 | umol/Kg | ALA905109 | umol.kg-1 | Mus musculus |