# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA395573 | 33 | IC50 | = | 18 | uM | ALA896225 | 4.75 | nM | Homo sapiens | ||
2. | ALA395573 | 33 | permeability | < | 5 | 10^-6 cm/s | ALA896221 | 10^-6 cm/s | ||||
3. | ALA395573 | 33 | Solubility | < | 10 | ug ml-1 | ALA896220 | ug.mL-1 | ||||
4. | ALA395573 | 33 | F | < | 1 | % | ALA896216 | % | Rattus norvegicus | |||
5. | ALA395573 | 33 | t1/2 | = | 4.2 | hr | ALA896215 | hr | Rattus norvegicus | |||
6. | ALA395573 | 33 | AUC/dose | < | 10 | ng.hr.kg/mg/ml | ALA896214 | ng.hr.kg/mg/ml | Rattus norvegicus | |||
7. | ALA395573 | 33 | t1/2 | = | 0.8 | hr | ALA896213 | hr | Rattus norvegicus | |||
8. | ALA395573 | 33 | Vss | = | 1.6 | L/Kg | ALA896212 | L.kg-1 | Rattus norvegicus | |||
9. | ALA395573 | 33 | CL | = | 38 | ml/min.kg | ALA896211 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896203 | nM | Homo sapiens | |||
11. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896202 | nM | Homo sapiens | |||
12. | ALA395573 | 33 | IC50 | = | 40.1 | uM | ALA896201 | 4.40 | nM | Homo sapiens | ||
13. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896200 | nM | Homo sapiens | |||
14. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896199 | nM | Homo sapiens | |||
15. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896198 | nM | Homo sapiens | |||
16. | ALA395573 | 33 | IC50 | > | 40 | uM | ALA896197 | nM | Homo sapiens | |||
17. | ALA395573 | 33 | Activity | = | 11400 | nM | ALA896196 | nM | Homo sapiens | |||
18. | ALA395573 | 33 | Activity | = | 1500 | nM | ALA896195 | nM | ||||
19. | ALA395573 | 33 | IC50 | = | 2900 | nM | ALA896194 | 5.54 | nM | Homo sapiens | ||
20. | ALA395573 | 33 | IC50 | = | 18 | nM | ALA896193 | 7.75 | nM | Homo sapiens |