| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA244936 | 42 | pKa_B1 | 10.09 | ALA3301362 | "B1 Functional Group: Piperidine; Ionisation Formula: A0B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 2. | ALA244936 | 42 | LogD7.4 | 3.3 | ALA3301363 | |||||||
| 3. | ALA244936 | 42 | IC50 | = | 0.052 | uM | ALA3227232 | 7.28 | nM | Homo sapiens | ||
| 4. | ALA244936 | 42 | CLint | 3.8 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
| 5. | ALA244936 | 42 | CLint | < | 3 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | ||||
| 6. | ALA244936 | 42 | Kbapp | = | 430 | nM | ALA895700 | nM | Homo sapiens | |||
| 7. | ALA244936 | 42 | E/Emax | = | 0 | % | ALA895699 | % | Homo sapiens | |||
| 8. | ALA244936 | 42 | IC50 | = | 9.6 | uM | ALA896832 | 5.02 | nM | Homo sapiens | ||
| 9. | ALA244936 | 42 | Solubility | = | 125 | uM | ALA896831 | nM | ||||
| 10. | ALA244936 | 42 | Ki | > | 1 | uM | ALA896830 | nM | Homo sapiens | |||
| 11. | ALA244936 | 42 | Cmax | 0 | ALA895702 | Not Determined | Rattus norvegicus | |||||
| 12. | ALA244936 | 42 | Ki | = | 110 | nM | ALA895698 | 6.96 | nM | Ovis aries |
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