| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA232827 | (S)-12 | Ratio IC50 | = | 420 | ALA892509 | ||||||
| 2. | ALA232827 | (S)-12 | Ratio IC50 | = | 600 | ALA892508 | Homo sapiens | |||||
| 3. | ALA232827 | (S)-12 | F | = | 100 | % | ALA893553 | % | Rattus norvegicus | |||
| 4. | ALA232827 | (S)-12 | AUC | = | 2.6 | hr.microg/ml | ALA893552 | ng.hr.mL-1 | Rattus norvegicus | |||
| 5. | ALA232827 | (S)-12 | AUC | = | 0.28 | ug ml-1 | ALA893551 | ug ml-1 | Rattus norvegicus | |||
| 6. | ALA232827 | (S)-12 | Cmax | = | 0.8 | μg/mL | ALA893550 | μg/mL | Rattus norvegicus | |||
| 7. | ALA232827 | (S)-12 | Vss | = | 21 | L/Kg | ALA893549 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA232827 | (S)-12 | CL | = | 128 | ml/min.kg | ALA893548 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA232827 | (S)-12 | t1/2 | = | 2.9 | hr | ALA893547 | hr | Rattus norvegicus | |||
| 10. | ALA232827 | (S)-12 | t1/2 | = | 2.2 | hr | ALA893546 | hr | Rattus norvegicus | |||
| 11. | ALA232827 | (S)-12 | Stability | = | 31 | % | ALA892507 | % | Homo sapiens | |||
| 12. | ALA232827 | (S)-12 | Stability | = | 89 | % | ALA893555 | % | ||||
| 13. | ALA232827 | (S)-12 | Stability | = | 47 | % | ALA893554 | % | Rattus norvegicus | |||
| 14. | ALA232827 | (S)-12 | IC50 | = | 72 | nM | ALA893545 | 7.14 | nM | Homo sapiens | ||
| 15. | ALA232827 | (S)-12 | IC50 | = | 9 | nM | ALA893544 | 8.05 | nM | Homo sapiens |
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