Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA249966	19	LogD7.4		0.75		ALA3301363
2.	ALA249966	19	Solubility		575.4	uM	ALA3301364		nM
3.	ALA249966	19	Selectivity ratio	>	10000		ALA1119725
4.	ALA249966	19	Selectivity ratio	>	1000		ALA1119724
5.	ALA249966	19	IC50	<	1	nM	ALA1119720		nM	Homo sapiens
6.	ALA249966	19	Activity		0		ALA980885	Non-toxic		Macaca fascicularis
7.	ALA249966	19	Activity		0		ALA980884	Active		Macaca fascicularis
8.	ALA249966	19	Activity		0		ALA980883	Active		Macaca fascicularis
9.	ALA249966	19	Activity		0		ALA980882	Active		Macaca fascicularis
10.	ALA249966	19	Activity		0		ALA980881	Active		Macaca fascicularis
11.	ALA249966	19	Activity		0		ALA980880	Active		Macaca fascicularis
12.	ALA249966	19	Activity		0		ALA980879	Active		Macaca fascicularis
13.	ALA249966	19	Drug uptake	=	34.9	nM	ALA980878		nM
14.	ALA249966	19	Drug uptake	=	33496	nM	ALA980877		nM
15.	ALA249966	19	Drug uptake	=	960	nM	ALA980876		nM	Rattus norvegicus
16.	ALA249966	19	Activity	=	73.2	%	ALA980875		%	Rattus norvegicus
17.	ALA249966	19	F	=	98	%	ALA980874		%	Rattus norvegicus
18.	ALA249966	19	Vdss	=	97.2	L/Kg	ALA980018		L.kg-1	Rattus norvegicus
19.	ALA249966	19	CL	=	14.3	L/hr/kg	ALA980016		mL.min-1.kg-1	Rattus norvegicus
20.	ALA249966	19	t1/2	=	4.7	hr	ALA980014		hr	Rattus norvegicus