Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1491	18, Amlodipine	inhibition	=	-5.75	%	ALA4808150			%	Homo sapiens
2.	ALA1491	18, Amlodipine	inhibition	=	-14.61	%	ALA4808149			%	Homo sapiens
3.	ALA1491	18, Amlodipine	Inhibition index	=	-0.108		ALA4303819				Severe acute respiratory syndrome coronavirus 2
4.	ALA1491	18, Amlodipine	FICI	=	0.017		ALA4194530
5.	ALA1491	18, Amlodipine	FICI	=	0.017		ALA4194529
6.	ALA1491	18, Amlodipine	CL free	=	85	ml/min.kg	ALA4181694			mL.min-1.kg-1	Homo sapiens
7.	ALA1491	18, Amlodipine	t1/2	=	40	hr	ALA4181692			hr	Homo sapiens
8.	ALA1491	18, Amlodipine	Drug uptake(free)	=	2	nM	ALA4181690			nM	Homo sapiens
9.	ALA1491	18, Amlodipine	IC50	=	2	nM	ALA4181688	8.70		nM
10.	ALA1491	18, Amlodipine	pIC50	<	4.7		ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
11.	ALA1491	18, Amlodipine	IC50	>	0	M	ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
12.	ALA1491	18, Amlodipine	inhibition	=	94.32	%	ALA4513082			%	Severe acute respiratory syndrome coronavirus 2
13.	ALA1491	18, Amlodipine	PPB		98.09	%	ALA3301365			%
14.	ALA1491	18, Amlodipine	beta t1/2	=	34	hr	ALA3591352			hr	Homo sapiens
15.	ALA1491	18, Amlodipine	CL	=	7	ml/min.kg	ALA3591351			mL.min-1.kg-1	Homo sapiens
16.	ALA1491	18, Amlodipine	Vdss	=	17	L/Kg	ALA3591349			L.kg-1	Homo sapiens
17.	ALA1491	18, Amlodipine	logD	=	1.2		ALA3591347
18.	ALA1491	18, Amlodipine	logP	=	3.3		ALA3591346
19.	ALA1491	18, Amlodipine	pKa	=	9.45		ALA3591345
20.	ALA1491	18, Amlodipine	IC50	>	10	uM	ALA3562043		inactive	nM