Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA253597	[11C]10	logD	=	2.82		ALA5104239
2.	ALA253597	[11C]10	IC50	=	8.07	nM	ALA5104238	8.09	nM	Homo sapiens
3.	ALA253597	[11C]10	Drug uptake	=	89.1	%	ALA926120		%	Rattus norvegicus
4.	ALA253597	[11C]10	Drug uptake	=	0.39	%	ALA926116		%	Rattus norvegicus
5.	ALA253597	[11C]10	Drug uptake	=	2.4	%	ALA926115		%	Rattus norvegicus
6.	ALA253597	[11C]10	Drug uptake	=	94.4	%	ALA926119		%	Rattus norvegicus
7.	ALA253597	[11C]10	Drug uptake	=	7	%	ALA926114		%	Rattus norvegicus
8.	ALA253597	[11C]10	Drug uptake	=	97.6	%	ALA926118		%	Rattus norvegicus
9.	ALA253597	[11C]10	Drug uptake	=	4.2	%	ALA926113		%	Rattus norvegicus
10.	ALA253597	[11C]10	Log D	=	3.01		ALA926121
11.	ALA253597	[11C]10	Drug uptake	=	66.8	%	ALA926112		%	Macaca mulatta
12.	ALA253597	[11C]10	Drug uptake	=	33.2	%	ALA924979		%	Macaca mulatta
13.	ALA253597	[11C]10	Stability	=	99	%	ALA926105		%
14.	ALA253597	[11C]10	Stability	=	99.8	%	ALA926104		%	Rattus norvegicus
15.	ALA253597	[11C]10	Stability	=	95.8	%	ALA926103		%	Macaca mulatta
16.	ALA253597	[11C]10	Fu	=	5.6	%	ALA924978			Macaca mulatta
17.	ALA253597	[11C]10	Ki	=	0.68	nM	ALA924980	9.17	nM	Rattus norvegicus
18.	ALA253597	[11C]10	Ki	=	0.944	nM	ALA924981	9.03	nM
19.	ALA253597	[11C]10	Ki	=	2.47	nM	ALA924983	8.61	nM	Homo sapiens
20.	ALA253597	[11C]10	Ki	=	2.2	uM	ALA924982	5.66	nM	Homo sapiens