# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Omeprazole | 1 (Omeprazole (Hassle)) | IC50 | < | 1 | uM | ALA5234343 | nM | Plasmodium | |||
2. | Omeprazole | 1 (Omeprazole (Hassle)) | IC50 | = | 2.08 | uM | ALA5167767 | 5.68 | nM | Homo sapiens | ||
3. | Omeprazole | 1 (Omeprazole (Hassle)) | Activity | = | 1.7 | log10CFU | ALA5135365 | log10CFU | Helicobacter pylori | |||
4. | Omeprazole | 1 (Omeprazole (Hassle)) | IC50 | = | 17.6 | uM | ALA5128699 | 4.75 | nM | Homo sapiens | ||
5. | Omeprazole | 1 (Omeprazole (Hassle)) | INH | 0 | ALA4422587 | Active | % | Homo sapiens | ||||
6. | Omeprazole | 1 (Omeprazole (Hassle)) | CLH | = | 162.6 | microL/min/mg | ALA4410700 | mL.min-1.g-1 | ||||
7. | Omeprazole | 1 (Omeprazole (Hassle)) | t1/2 | = | 8.5 | min | ALA4410699 | hr | ||||
8. | Omeprazole | 1 (Omeprazole (Hassle)) | CLH | = | 162.6 | uL/min/ug | ALA4409667 | mL.min-1.g-1 | ||||
9. | Omeprazole | 1 (Omeprazole (Hassle)) | t1/2 | = | 8.5 | min | ALA4409666 | hr | ||||
10. | Omeprazole | 1 (Omeprazole (Hassle)) | INH | = | 41 | % | ALA4399082 | % | Homo sapiens | |||
11. | Omeprazole | 1 (Omeprazole (Hassle)) | inhibition | = | -3.93 | % | ALA4808150 | % | Homo sapiens | |||
12. | Omeprazole | 1 (Omeprazole (Hassle)) | inhibition | = | -14.59 | % | ALA4808149 | % | Homo sapiens | |||
13. | Omeprazole | 1 (Omeprazole (Hassle)) | LD50 | = | 544 | nM | ALA4774457 | nM | Giardia intestinalis | |||
14. | Omeprazole | 1 (Omeprazole (Hassle)) | LD50 | = | 116 | nM | ALA4774456 | nM | Giardia intestinalis | |||
15. | Omeprazole | 1 (Omeprazole (Hassle)) | LD50 | = | 116 | nM | ALA4774455 | nM | Giardia intestinalis | |||
16. | Omeprazole | 1 (Omeprazole (Hassle)) | Hit score | = | 0.176 | ALA4303810 | Severe acute respiratory syndrome coronavirus 2 | |||||
17. | Omeprazole | 1 (Omeprazole (Hassle)) | Selectivity index | > | 2.35 | ALA4303822 | ||||||
18. | Omeprazole | 1 (Omeprazole (Hassle)) | CC50 | > | 40 | uM | ALA4303821 | nM | Chlorocebus sabaeus | |||
19. | Omeprazole | 1 (Omeprazole (Hassle)) | EC90 | = | 38.01 | uM | ALA4303820 | uM | Severe acute respiratory syndrome coronavirus 2 | |||
20. | Omeprazole | 1 (Omeprazole (Hassle)) | EC50 | = | 17.06 | uM | ALA4303820 | 4.77 | nM | Severe acute respiratory syndrome coronavirus 2 |