# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA757 | N-1 | Potency | 33.498 | uM | ALA2354254 | inconclusive | nM | Homo sapiens | |||
2. | ALA757 | N-1 | Potency | 29.093 | uM | ALA2354254 | inconclusive | nM | Homo sapiens | |||
3. | ALA757 | N-1 | Potency | 0.073 | uM | ALA2114780 | inactive | nM | Homo sapiens | |||
4. | ALA757 | N-1 | Potency | 35.481 | uM | ALA2114775 | inconclusive | nM | ||||
5. | ALA757 | N-1 | Potency | 26.609 | uM | ALA2354221 | inconclusive | nM | Homo sapiens | |||
6. | ALA757 | N-1 | Potency | 23.109 | uM | ALA2354221 | inconclusive | nM | Homo sapiens | |||
7. | ALA757 | N-1 | Potency | 29.855 | uM | ALA2354221 | inconclusive | nM | Homo sapiens | |||
8. | ALA757 | N-1 | AC50 | 2.818 | uM | ALA3562119 | inactive | nM | ||||
9. | ALA757 | N-1 | log(RBA) | = | 1.6 | ALA3281645 | ||||||
10. | ALA757 | N-1 | log(RBA) | = | 1 | ALA3281644 | Oryctolagus cuniculus | |||||
11. | ALA757 | N-1 | log(RBA) | = | 1 | ALA3281643 | Ovis aries | |||||
12. | ALA757 | N-1 | log(RBA) | = | 1.14 | ALA3281642 | Homo sapiens | |||||
13. | ALA757 | N-1 | Hepatotoxicity (mechanism) | 0 | ALA3137740 | |||||||
14. | ALA757 | N-1 | Hepatotoxicity (time to onset) | 0 | ALA3137739 | 4 months - 12 years | ||||||
15. | ALA757 | N-1 | Hepatotoxicity (comment) | 0 | ALA3137738 | CHOLESTASE_PROLONGEE | ||||||
16. | ALA757 | N-1 | Hepatotoxicity (successful reintroduction) | 0 | ALA3137737 | |||||||
17. | ALA757 | N-1 | Hepatotoxicity (animal toxicity known) | 0 | ALA3137736 | |||||||
18. | ALA757 | N-1 | Hepatotoxicity (benign tumour) | = | 2 | ALA3137735 | references out of a total of 10 | |||||
19. | ALA757 | N-1 | Hepatotoxicity (malignant tumour) | = | 0 | ALA3137734 | references out of a total of 10 | |||||
20. | ALA757 | N-1 | Hepatotoxicity (steatosis) | = | 1 | ALA3137733 | references out of a total of 10 |