| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA254370 | 15 | IC50 | = | 6.8 | nM | ALA5215021 | 8.17 | nM | Homo sapiens | ||
| 2. | ALA254370 | 15 | CLint | 65 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
| 3. | ALA254370 | 15 | Solubility | 645.7 | uM | ALA3301364 | nM | |||||
| 4. | ALA254370 | 15 | LogD7.4 | 2.14 | ALA3301363 | |||||||
| 5. | ALA254370 | 15 | CLint | < | 3 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | ||||
| 6. | ALA254370 | 15 | IC50 | = | 48 | nM | ALA912820 | 7.32 | nM | Homo sapiens | ||
| 7. | ALA254370 | 15 | IC50 | = | 398 | nM | ALA912819 | 6.40 | nM | Homo sapiens | ||
| 8. | ALA254370 | 15 | AUC | = | 17.4 | uM.hr | ALA912817 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 9. | ALA254370 | 15 | IC50 | = | 254 | nM | ALA912816 | 6.59 | nM | Homo sapiens | ||
| 10. | ALA254370 | 15 | IC50 | = | 6.8 | nM | ALA909848 | 8.17 | nM | Homo sapiens | ||
| 11. | ALA254370 | 15 | AUC | = | 17.4 | uM.hr | ALA1055930 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 12. | ALA254370 | 15 | Ki | = | 4.4 | nM | ALA1055929 | 8.36 | nM | Homo sapiens | ||
| 13. | ALA254370 | 15 | Ki | = | 40 | nM | ALA1055928 | 7.40 | nM | Homo sapiens | ||
| 14. | ALA254370 | 15 | Ki | = | 40 | nM | ALA963306 | 7.40 | nM | Homo sapiens | ||
| 15. | ALA254370 | 15 | AUC | = | 17.4 | uM.hr | ALA963307 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 16. | ALA254370 | 15 | Ki | = | 4 | nM | ALA963305 | 8.40 | nM | Homo sapiens | ||
| 17. | ALA254370 | 15 | Ki | = | 4.7 | nM | ALA929862 | 8.33 | nM | Homo sapiens | ||
| 18. | ALA254370 | 15 | IC50 | = | 6.8 | nM | ALA929862 | 8.17 | nM | Homo sapiens |
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