| 1. |  3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 42.7 | uM | ALA3382307 | 4.37 | | nM | |
| 2. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 24 | uM | ALA3382308 | 4.62 | | nM | |
| 3. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.029 | uM | ALA3382309 | 7.54 | | nM | |
| 4. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ratio Ki | = | 1.1 | | ALA4330003 | | | | |
| 5. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.19 | uM | ALA4330002 | 6.72 | | nM | Homo sapiens |
| 6. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.18 | uM | ALA4330001 | 6.75 | | nM | Homo sapiens |
| 7. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.27 | uM | ALA2388711 | 6.57 | | nM | Homo sapiens |
| 8. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.29 | uM | ALA2388710 | 6.54 | | nM | Homo sapiens |
| 9. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 280 | nM | ALA2343415 | 6.55 | | nM | |
| 10. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | FC | = | 2.5 | | ALA2343414 | | | | |
| 11. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | INH | | 0 | | ALA1250605 | | Active | % | Homo sapiens |
| 12. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | INH | | 0 | | ALA1251514 | | Active | % | Homo sapiens |
| 13. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Activity | | 0 | | ALA1251512 | | Active | | Homo sapiens |
| 14. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Activity | | 0 | | ALA1251511 | | Active | | Homo sapiens |
| 15. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Activity | | 0 | | ALA1251513 | | Not Active | | Mus musculus |
| 16. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Activity | | 0 | | ALA1251509 | | Active | | Homo sapiens |
| 17. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Activity | | 0 | | ALA1251508 | | Active | | Homo sapiens |
| 18. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | INH | = | 43 | % | ALA1251510 | | | % | Mus musculus |
| 19. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 20 | uM | ALA1251507 | 4.70 | | nM | |
| 20. | 3a,6,7,7a-Tetrahydro-5-(hydroxymethyl)-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diol | 1a, GlcNAc-thiazoline | Ki | = | 0.01 | uM | ALA1251506 | 8.00 | | nM | Homo sapiens |
