# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA256105 | monensin | % maximum response | = | 52.2 | % | ALA1908292 | Calcein-AM Inhibitor: Y | % | Homo sapiens | ||
2. | ALA256105 | monensin | Ratio_ATPase activity | = | 6.71 | ALA1908291 | ATPase Activator: Y | Homo sapiens | ||||
3. | ALA256105 | monensin | Ratio_Papp | = | 2.88 | ALA1908289 | Effluxed: Y | Homo sapiens | ||||
4. | ALA256105 | monensin | Papp | = | 294 | nm/s | ALA1908286 | nm/s | Homo sapiens | |||
5. | ALA256105 | monensin | Papp | = | 102 | nm/s | ALA1908285 | nm/s | Homo sapiens | |||
6. | ALA256105 | monensin | GI | = | 50 | % | ALA2216062 | % | Homo sapiens | |||
7. | ALA256105 | monensin | GI | = | 50 | % | ALA2216061 | % | ||||
8. | ALA256105 | monensin | FC | = | 100 | ALA2216060 | ||||||
9. | ALA256105 | monensin | FC | = | 2 | ALA2216059 | ||||||
10. | ALA256105 | monensin | NOAEL | = | 2 | mg kg-1 | ALA2216057 | mg kg-1 | Rattus norvegicus | |||
11. | ALA256105 | monensin | NOAEL | = | 1.25 | mg/kg/day | ALA2216058 | mg/kg/day | Canis lupus familiaris | |||
12. | ALA256105 | monensin | NOAEL | = | 1.4 | mg/kg/day | ALA2216056 | mg/kg/day | Rattus norvegicus | |||
13. | ALA256105 | monensin | NOAEL | = | 1.3 | mg/kg/day | ALA2216055 | mg/kg/day | Mus musculus | |||
14. | ALA256105 | monensin | NOAEL | = | 5 | mg/kg/day | ALA2216054 | mg/kg/day | Canis lupus familiaris | |||
15. | ALA256105 | monensin | Ratio IC50 | = | 232.11 | ALA3619941 | ||||||
16. | ALA256105 | monensin | Ratio IC50 | = | 0.56 | ALA3619940 | Homo sapiens | |||||
17. | ALA256105 | monensin | Ratio IC50 | = | 34.25 | ALA3619939 | ||||||
18. | ALA256105 | monensin | Ratio IC50 | = | 19.17 | ALA3619938 | ||||||
19. | ALA256105 | monensin | IC50 | = | 20.89 | uM | ALA3619937 | 4.68 | nM | Mus musculus | ||
20. | ALA256105 | monensin | IC50 | = | 0.09 | uM | ALA3619936 | 7.05 | nM | Homo sapiens |