| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA261592 | 13, BMS-645737 | F | = | 68 | % | ALA925776 | % | Rattus norvegicus | |||
| 2. | ALA261592 | 13, BMS-645737 | AUC | = | 287 | uM | ALA925777 | uM | Rattus norvegicus | |||
| 3. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA925778 | Non-toxic | Mus musculus | |||||
| 4. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA925779 | Non-toxic | Mus musculus | |||||
| 5. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA925780 | Non-toxic | Mus musculus | |||||
| 6. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA926793 | Non-toxic | Mus musculus | |||||
| 7. | ALA261592 | 13, BMS-645737 | PPB | = | 97.2 | % | ALA925775 | % | Rattus norvegicus | |||
| 8. | ALA261592 | 13, BMS-645737 | MED | = | 7.5 | mg kg-1 | ALA929448 | mg kg-1 | Homo sapiens | |||
| 9. | ALA261592 | 13, BMS-645737 | Activity | >= | 50 | % | ALA925774 | % | Homo sapiens | |||
| 10. | ALA261592 | 13, BMS-645737 | Activity | >= | 50 | % | ALA925773 | % | Homo sapiens | |||
| 11. | ALA261592 | 13, BMS-645737 | AUC | = | 30 | uM.hr | ALA925772 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 12. | ALA261592 | 13, BMS-645737 | Cmax | = | 2.64 | uM | ALA925771 | nM | Mus musculus | |||
| 13. | ALA261592 | 13, BMS-645737 | AUC | = | 11 | uM.hr | ALA925770 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 14. | ALA261592 | 13, BMS-645737 | Cmax | = | 1.03 | uM | ALA936660 | nM | Mus musculus | |||
| 15. | ALA261592 | 13, BMS-645737 | Activity | 0 | ALA929448 | Dose-dependent effect | Homo sapiens | |||||
| 16. | ALA261592 | 13, BMS-645737 | IC50 | > | 10000 | nM | ALA929447 | nM | ||||
| 17. | ALA261592 | 13, BMS-645737 | IC50 | > | 10000 | nM | ALA929446 | nM | ||||
| 18. | ALA261592 | 13, BMS-645737 | IC50 | > | 10000 | nM | ALA929445 | nM | Homo sapiens | |||
| 19. | ALA261592 | 13, BMS-645737 | IC50 | > | 2500 | nM | ALA929444 | nM | Homo sapiens | |||
| 20. | ALA261592 | 13, BMS-645737 | IC50 | = | 138 | nM | ALA929443 | 6.86 | nM | Homo sapiens |
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