| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Penciclovir | 3 Penciclovir | AC50 | > | 30 | uM | ALA5291731 | Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">") | nM | Homo sapiens | ||
| 2. | Penciclovir | 3 Penciclovir | AC50 | > | 30 | uM | ALA5291887 | Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">") | nM | Homo sapiens | ||
| 3. | Penciclovir | 3 Penciclovir | Selectivity Index | > | 4.17 | ALA5245813 | ||||||
| 4. | Penciclovir | 3 Penciclovir | CC50 | > | 400 | uM | ALA5245812 | nM | Chlorocebus sabaeus | |||
| 5. | Penciclovir | 3 Penciclovir | EC50 | = | 95.96 | uM | ALA5245811 | 4.02 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
| 6. | Penciclovir | 3 Penciclovir | EC50 | = | 95.96 | uM | ALA5227048 | 4.02 | nM | Severe acute respiratory syndrome-related coronavirus | ||
| 7. | Penciclovir | 3 Penciclovir | CC50 | > | 400 | uM | ALA5227009 | nM | Chlorocebus sabaeus | |||
| 8. | Penciclovir | 3 Penciclovir | IC50 | > | 394.85 | uM | ALA3392941 | nM | Trypanosoma brucei rhodesiense | |||
| 9. | Penciclovir | 3 Penciclovir | IC50 | = | 254.28 | uM | ALA3392937 | nM | Trypanosoma cruzi | |||
| 10. | Penciclovir | 3 Penciclovir | IC50 | > | 394.85 | uM | ALA3392942 | nM | Leishmania donovani | |||
| 11. | Penciclovir | 3 Penciclovir | IC50 | > | 118.45 | uM | ALA3392943 | nM | Leishmania donovani | |||
| 12. | Penciclovir | 3 Penciclovir | IC50 | = | 169.39 | uM | ALA3392944 | nM | Plasmodium falciparum | |||
| 13. | Penciclovir | 3 Penciclovir | IC50 | = | 219.54 | uM | ALA3392938 | nM | ||||
| 14. | Penciclovir | 3 Penciclovir | IC50 | > | 118.45 | uM | ALA3392939 | nM | ||||
| 15. | Penciclovir | 3 Penciclovir | pKa_B1 | 2.97 | ALA3301362 | "B1 Functional Group: 9H-purin-6-ol, 2-amino-; Ionisation Formula: A1B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 16. | Penciclovir | 3 Penciclovir | pKa_A1 | 9.48 | ALA3301375 | "A1 Functional Group: 9H-purin-6-ol, 2-amino-; Ionisation Formula: A1B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 17. | Penciclovir | 3 Penciclovir | AC50 | 0.631 | uM | ALA3562146 | inactive | nM | ||||
| 18. | Penciclovir | 3 Penciclovir | Ac50 | 0.631 | uM | ALA3562152 | inactive | uM | ||||
| 19. | Penciclovir | 3 Penciclovir | Potency | 0.708 | uM | ALA3562110 | inactive | nM | Homo sapiens | |||
| 20. | Penciclovir | 3 Penciclovir | Ratio | = | 23 | uL/min | ALA3528441 | uL/min | Homo sapiens |
The page will load shortly, Thanks for your patience!